Taking a closer look at atypical Addison’s

How to spot the great pretender

The West Highland white terrier is one of the breeds genetically predisposed to Addison's disease (HOC). Photo courtesy Samantha Ashenhurst.
 Dogs with “classic” hypoadrenocorticism (HOC), aka Addison’s disease, manifest clinical signs reflecting deficiencies in both cortisol and aldosterone. These patients are relatively easily identified, often based on predictable electrolyte derangements. However, we are now increasingly recognizing a subset of dogs with hypoadrenocorticism, but normal electrolytes.1-3 Clinical signs in these patients reflect hypocortisolemia only, and are often subtler and more insidious. This condition is referred to as glucocorticoid deficient HOC (GDHOC) or “atypical” Addison’s/hypoadrenocorticism (AHOC).



You’ve landed on a members-only feature.

If you are already a member, please log in below.

Join VPN Plus+ today to get access to this feature and more like:

  • Members-only content:
    •   In-depth case studies
    •   New protocols
    •   Detailed practice management strategies
    •   More from some of your favorite columnists like Patty Khuly and Brennen McKenzie
    •   Exclusive webinars, roundtables and videos
  • And additional benefits including:
    •   VIP discounts to VetMedTeam online education and VetCE events
    •   An annual ‘Vet Box’ full of curated products just for you!