By Sarah Boston, DVM, DVSc, Dipl. ACVS
Mast cell tumors (MCT) are one of the most common skin tumors seen in dogs.1 These tumors can vary widely in appearance and biological behavior. MCTs are easily diagnosed with fine needle aspirate and cytology. Tumor grade, which is currently determined with histopathology, predicts behavior. The Patnaik three-tier grading scheme has largely been replaced with the Kiupel scheme, which designates these tumors as either low-grade or high-grade.2 Low-grade tumors have an excellent prognosis with effective local control and are unlikely to metastasize to other sites, whereas high-grade tumors are more difficult to control locally and have a higher chance of metastasis.2
Common sites of metastasis include the draining lymph node, spleen, ...
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