Managing sepsis

Looking at a rational approach and a cautionary tale

Oranges are a proven source of vitamin C, but is vitamin C a proven treatment for sepsis in animals? Photo: sam-21/Bigstock
Sepsis is currently defined as a life-threatening organ dysfunction secondary to a dysregulated physiologic response to infection. There are widely used, evidence-based guidelines for diagnosing and managing sepsis in human medicine,1 but there is no single guideline or consensus statement on sepsis management in veterinary medicine. The guidelines most veterinarians follow, and those which we use at my hospital, are derived from expert opinion and the adaptation of human sepsis protocols employed at several academic veterinary institutions.
Managing sepsis is a great example of the challenge of practicing evidence-b...


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