Sleepypod Offers to Replace Crash-Damaged Travel GearDecember 23, 2014Sleepypod, whose dog travel harnesses have won top marks, is offering a free replacement or discounted pricing when a pet carrier or safety harness is damaged in a traffic accident. The program extends to competitors’ equipment as well. The burden of proof falls on pet owners, who must provide a police report and photos and answer a questionnaire. Damaged Sleepypod products are eligible for no-charge replacement—other than shipping costs—while owners of other brands may receive 30 percent off the Pasadena, Calif., company’s selection of mobile pet beds, carriers and harnesses. “Sleepypod wants to ensure pet safety after an auto accident,” said co-founder and lead product designer Michael Leung. “The integrity of a pet safety restraint may be compromised during an auto accident, so it is critical to inspect a pet carrier or harness for damage before being reused.” Damage may include anything from broken stitches and zippers to torn webbing. “If the accident is severe enough, webbing could be stretched, and therefore weaken the material,” Leung said. More information about the replacement program, which was announced Dec. 18, is available at www.sleepypod.com/accident-replacement-program. The nonprofit Center for Pet Safety, which conducts crash-testing, has deemed Sleepypod’s Clickit Sport …
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Jaguar Seeks Limited Approval of Canine Diarrhea DrugDecember 22, 2014The startup drug company Jaguar Animal Health today reported the filing of its first New Animal Drug Application (NADA) with the U.S. Food and Drug Administration. If approved, the drug Canalevia would be used to treat dogs stricken with watery diarrhea during chemotherapy. Jaguar described Canalevia as a first-in-class anti-secretory agent intended for use in multiple animal species. The NADA filing requests Minor Use/Minor Species (MUMS) status for dogs as the drug undergoes further study. The limited designation would allow Jaguar to distribute Canalevia “before collecting all necessary effectiveness data, but after proving the drug is safe and showing that there is a reasonable expectation of effectiveness,” the San Francisco company stated. The decision to pursue MUMS status followed a meeting Oct. 22 between Jaguar and FDA representatives, according to the company. “[The] approach … will allow us to bring this new tool for management of certain chemotherapy side effects to dogs in need as soon as possible,” Jaguar reported. Canalevia contains crofelemer, an antidiarrheal found in the Croton lechleri tree and used to treat HIV-associated diarrhea in people. Jaguar in September launched its first non-prescription product, Neonorm Calf, for the treatment of watery diarrhea, or scours, in …
Aratana Moves Ahead on 2 Canine DrugsDecember 19, 2014A drug being studied for the treatment of osteoarthritis pain in dogs showed positive results in a pivotal field study, according to the developer, Aratana Therapeutics Inc. The Kansas City, Kan., veterinary drug maker also announced the launch of a pivotal field effectiveness study for a drug formulated to treat post-surgical pain in dogs. The osteoarthritis drug, code-named AT-001, was used in a blinded, placebo-controlled, multicenter dose-ranging study involving 280 client-owned dogs. The dogs, all of whom had osteoarthritis, were split into AT-001 and placebo groups and received daily oral doses for 28 days, Aratana reported Thursday. Validated owner-assessed pain scores showed that AT-001, which uses the compound grapiprant to target the EP4 receptor, demonstrated statistically significant improvements compared with the placebo, Aratana noted. The company expects to win U.S. Food and Drug Administration approval of AT-001 in 2016. “We believe AT-001 has the potential to be an important product in the well-established pain market,” said President and CEO Steven St. Peter, MD. Aratana also reported the initiation of a pivotal field effectiveness study of a drug licensed from Pacira Pharmaceuticals Inc. of Parsippany, N.J. AT-003 is an injectable, extended-release bupivacaine formulated for post-operative pain in dogs. A …
AKC Foundation Honors 6 Research FundraisersDecember 15, 2014Six organizations that over the past 20 years combined to donate more than $3.3 million to the American Kennel Club’s Canine Health Foundation have been named Distinguished Research Partners. Recognized Dec. 11 during the foundation’s Canine & Cocktails event in Orlando, Fla., were the Orthopedic Foundation for Animals, the Irish Setter Club of America Foundation, the Newfoundland Club of America Charitable Trust, the Collie Health Foundation, the Golden Retriever Foundation and the American Boxer Charitable Foundation. The amounts raised by the groups to assist with canine research ranged from the Irish Setter Club’s $131,100 to the American Boxer foundation’s $1,180,130. “These clubs and organizations are making a lasting impact on canine health,” said Shila Nordone, MS, Ph.D., the Canine Health Foundation’s chief scientific officer. “Their donations … are supporting research that addresses some of the most prominent health concerns for our dogs. We are tackling cancer, subaortic stenosis, hypothyroidism, degenerative myelopathy, epilepsy, bloat and cardiomyopathy. “Together, we are working to provide better treatments and more accurate diagnoses for all dogs.” The Canine Health Foundation, a grant-making institution, will celebrate its 20th anniversary in 2015. The foundation also honored Thomas A. Grabe, publisher of The Canine Chronicle, with …
$500,000 Dog Park Debuts in Prescott, Ariz.December 12, 2014What does $500,000 buy? In Prescott, Ariz., that amount of cash has given the community a renovated dog park done up in a firefighter theme. Prescott’s Willow Creek Dog Park was chosen for a half-million-dollar makeover a year ago when resident Linda Nichols won the annual Beneful Dream Dog Park Contest, a competition sponsored by pet food maker Nestlé Purina PetCare Co. Months of work were unveiled Wednesday as Nichols was joined by project managers Jason Cameron, host of the TV shows “Desperate Landscapes,” “Man Caves” and “Sledgehammer,” and pet expert Arden Moore. Nichols and more than 1,000 other dog owners nationwide entered the contest. Nichols’ winning entry was selected from among 14 finalists after a round of judging and public voting. Moore, whose task was to oversee the project from a dog’s point of view, helped bring to life Nichols’ wish for a firefighter theme. Today dogs can race around a miniature red fire truck, run though giant fire truck tires, rest in a covered firehouse lounge and cool off next to fire hydrant misters. The makeover fixed what Nichols described in her contest video as a “large, fenced dirt field with lots of weeds.” Prescott …
Canine Breed-Specific Considerations for AnesthesiaDecember 8, 2014Originally published in the August 2014 issue of Veterinary Practice News The practice of mating individuals with desirable physical characteristics and/or the ability to excel at performing specific tasks has led to the development of over 170 recognized dog breeds in the United States.1 This large variety of dog breeds translates to a very diverse patient population for veterinarians; one may have to anesthetize a great Dane and Chihuahua in the same day. Owners and dog breeders will often express concern about their particular breeds being sensitive to anesthesia; however, there is only one breed–specific anesthetic sensitivity that is supported by scientific evidence: greyhounds. Even though a particular breed may not have a true anesthetic sensitivity, that breed may still warrant specific anesthetic considerations. By selecting for specific traits in dogs we have inadvertently or purposely created unique anatomic, physiologic and metabolic characteristics that may ultimately affect how a given dog is able respond to general anesthesia. An excellent example of this is English bulldog. Shutterstock Greyhounds (and other sighthounds?) Sensitive to thiopental Prolonged recovery from propofol and other drugs The greyhound is the only breed with a documented breed-specific sensitivity to particular anesthetic drugs. Greyhounds have prolonged …
N.J. Hospital Provides Free Care to Military K9sNovember 18, 2014Four-legged military veterans are eligible for free specialty veterinary care under a partnership established between a New Jersey hospital chain, the American Humane Association and the United States War Dogs Association. The arrangement, announced Nov. 11 in honor of Veterans Day, recognizes the dogs’ months or years of service overseas on behalf of the U.S. military. Red Bank Veterinary Hospital, which has five New Jersey locations, will provide free specialty care to retired military working dogs and contract working dogs. The latter group is made up of canines supplied to the military by contractors. “For more than 25 years, Red Bank Veterinary Hospital has been a leader in providing veterinary care to the animals of New Jersey, but we now want to be known as the leader in veterinary care for our veteran dogs,” said hospital co-founder Anthony DeCarlo, VMD. The sponsors estimated that each dog saved the lives of up to 200 soldiers by uncovering bombs and weapons caches while working in war zones such as Iraq and Afghanistan. “Dogs are as essential to the military as humans, but unlike humans, these dogs are not guaranteed medical care following their retirement,” said Ron Aiello, president of the War …
Researchers Hope to Lick Canine Gum DiseaseNovember 17, 2014The American Kennel Club’s Canine Health Foundation has awarded more than $25,000 for studies of two potential solutions to periodontal disease in dogs. Paola Massari, Ph.D., of Boston Medical Center will investigate a vaccine that would use a dog’s immune system to fight the bacteria responsible for gum disorders leading to tooth loss and pain. Django Martel, DVM, of the Animal Medical Center in New York will work with colleagues to determine whether antibiotic gel therapy can reduce periodontal disease, the Raleigh, N.C.-based foundation reported. Periodontal disease is a common condition in adult dogs. Most canines show evidence of periodontal disease and associated discomfort by age 3, the foundation noted. “Just like … in humans, periodontal disease in dogs is a painful condition that profoundly affects quality of life and can lead to a multitude of health problems,” said the foundation’s chief scientific officer, Shila Nordone, MS, Ph.D. “We have strategically funded research that will have immediate impact by supporting the evidence-based use of antibiotic gels to treat progressive disease, while also funding research that will provide a long-term solution by developing an effective vaccine to prevent the disease from occurring in the first place,” she said. Each …
Why You Should Keep Pulpitis in Mind When Treating A Discolored ToothNovember 14, 2014Originally published in the November 2014 issue of Veterinary Practice News Case Discussion Tasha, an 18- month-old female Labrador retriever, recently was presented to me for a discolored right maxillary canine tooth (Figure 1). The discoloration was intrinsic, imparting a gray color to the entire crown. The enamel of the crown was devoid of any defects, cracks or fractures. Differential Diagnoses A tooth may be discolored due to abnormal formation of enamel, such as enamel hypoplasia or hypomineralization. However, this tooth’s enamel was normal in thickness and texture. Exposure to the tetracycline family of antibiotics early in life can result in generalized discoloration of the teeth, but since only one tooth was discolored, a non-vital tooth secondary to pulpitis was most likely in Tasha’s case. What Causes Pulpitis? Pulpitis is inflammation of the pulp, which occurs most commonly due to blunt trauma to a tooth. This trauma may be caused by the patient bumping the tooth on something or biting down hard on something in a way that traumatizes the tooth without causing a fracture of the crown or root. The colors seen with pulpitis—pink, purple, gray, brown—are due to trauma to blood vessels within the tooth, which results in leakage …
How to Diagnose and Treat Uroabdomen CasesNovember 3, 2014Tucker, a 3-year-old border collie, was rushed to your hospital after getting hit by a car at 9 a.m. He is lucky, as he escaped without any fracture or major laceration. He only seems to have a few skin scrapes. You stabilize Tucker throughout the day, and he looks much better by that evening. He is kept overnight for IV fluids and pain medications. By the next morning, you are disappointed to see that Tucker’s condition has worsened overnight. Blood work and abdominal X-rays make you strongly suspect a bladder rupture. Ultrasound confirms it without a doubt. Fortunately, Dr. Jennifer Stafford, a double-boarded colleague in critical care and internal medicine at VCA Veterinary Referral Associates in Gaithersburg, Md., comes to the rescue with a full write-up on uroabdomen (JR Stafford, et al. “A clinical review of pathophysiology, diagnosis, and treatment of uroabdomen in the dog and cat.” J Vet Emerg Crit Care 2013, Vol 23, N 2, p. 216-229). As in Tucker’s case, most uroabdomen cases are caused by blunt trauma to the abdomen, such as getting hit by a car. The chances of this happening depend on the degree of bladder distention at the time of the trauma. Uroabdomen …
