FDA authorizes emergency use of drug to treat New World Screwworm in dogsOctober 28, 2025The agency concluded that “based on the scientific evidence available, it is reasonable to believe that Credelio may be effective in treating New World screwworm (NWS) infestations in dogs and puppies and the known and potential benefits of the product outweigh its known and potential risks.”
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Elanco announces FDA approval of new flea, tick preventiveJanuary 24, 2018Elanco Animal Health, a division of Eli Lilly and Co., announced that Credelio has been approved by the FDA. Credelio is a new monthly oral tick and flea option for dogs that contains the patented active ingredient lotilaner, which targets the nervous system receptors of ticks and fleas, not dogs, according to the company. The preventive protects against lone star, American dog, black-legged, and brown dog ticks, as well as fleas. "When choosing pet medications, veterinarians and pet owners are most concerned with safety for the pet as well as efficacy of the product. Lotilaner, the active ingredient in Credelio, was selected from hundreds of candidate molecules with this in mind," said Tony Rumschlag, DVM, director, regional consulting for Elanco. "This new tasty chewable is fast-acting and effective against ticks and fleas, while being easy on dogs and puppies." In a field study, 100 percent of Credelio tablets were administered successfully and dogs accepted 94 percent of them when offered by hand, in an empty bowl, or with food, according to the company. The product's active ingredient—lotilaner—circulates in the dog's blood stream, targeting the receptors of ticks and fleas when they bite the dog. In clinical studies, it killed 100 …
