Merck Releases 12-Week Flea, Tick Medicine

Bravecto (fluralaner) tablets for dogs kill fleas and multiple tick species for 12 weeks in a single dose.


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Bravecto is effective against fleas and four types of ticks.

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Many oral and spot-on products carry efficacy claims of up to 30 days. Merck reported that the U.S. Food and Drug Administration approved the new Bravecto (fluralaner) chewable tablets for dogs as the first and only treatment shown to kill fleas and multiple tick species for 12 weeks in a single dose.Merck Animal Health today upped the ante in the world of flea and tick preventives with a flavored chew proven to be effective for 12 weeks at a time.

"Bravecto is a breakthrough innovation that offers pet owners and veterinarians something that no other product does—the longest-lasting oral flea and tick prevention currently available," said KJ Varma, senior vice president of research and development at Summit, N.J.-based Merck.

The product is indicated to kill fleas for 12 weeks, the black-legged tick, American dog tick and brown dog tick for 12 weeks, and the Lone Star tick for eight weeks. The 12-week claims do not apply to dogs less than 6 months old.

The active ingredient, fluralaner, is a new ectoparasiticide belonging to the isoxazoline group, Merck noted.

The chew may be given to help control flea allergy dermatitis, the manufacturer added.

Bravecto's five dosages are based on a dog's weight: 4.4 to 9.9 pounds, 9.9 to 22 pounds, 22 to 44 pounds, 44 to 88 pounds and 88 to 123 pounds.

Clinical trials revealed the most common adverse reactions to be vomiting, decreased appetite, diarrhea, lethargy, polydipsia and flatulence.

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