NexGard Approved to Fight Brown Dog TicksApril 16, 2015Brown dog ticks, beware. Merial Ltd. has won permission from the U.S. Food and Drug Administration to add a label claim stating that the canine medication NexGard (afoxolaner) protects against a fourth tick species. The monthly preventive’s newest target is the brown dog tick (Rhipicephalus sanguineus), which is found throughout the lower 48 states and is linked to diseases such as Rocky Mountain spotted fever, anaplasmosis and ehrlichiosis. The Duluth, Ga., veterinary drug manufacturer in 2014 was allowed to promote NexGard’s effectiveness against black-legged (Ixodes scapularis) and lone star (Amblyomma americanum) ticks in addition to the initial claim for the American dog tick (Dermacentor variabilis). The prescription-only chewable tablet also is indicated to kill fleas. “When used as directed, NexGard has been shown to kill ticks all month long,” said Merial’s director of veterinary medical affairs, Doug Carithers, DVM. “Plus, it has the added benefit of killing fleas.” NexGard is not the only canine drug formulated to kill four common tick species. Merck Animal Health last year released a similar medication, Bravecto (fluralaner). Nexgard recently was named a 2015 Best New Product in the household category as part of a consumer survey conducted by Better Homes …
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Canine Infectious Respiratory Disease or Canine Influenza hits MidwestApril 8, 2015You’ve seen the news: Canine Infectious Respiratory Disease (CIRD) has hit Illinois, Wisconsin and Indiana, with 5 dogs reported dead and thousands more infected. The Chicago Veterinary Medical Association (CVMA) is recommending that dog owners take immediate, precautionary measures to prevent exposure to the virus. Dr. Donna Alexander, director of Cook County Department of Animal and Rabies Control has been reviewing data on the flu and stated, “The summary of those hospitals that reported through the CVMA to our offices and those who reported directly to this office indicates that 73% of those responding note an increase in CIRD. For those that supplied exact number of animals, we can report that there have been 1,013 cases of CIRD since January and 5 mortalities. The age of the animals presenting vary but show more severe forms in dogs under 1 year of age and greater than 7 years of age. Few veterinarians are submitting diagnostic specimens for evaluation. Of those submitted for PCR or other testing, the majority came back negative, some are still pending. Of those reporting positive, 93% are positive for canine influenza.” The American Veterinary Medical Association (AVMA) describes canine influenza as “a highly …
Find Out Why Once Every Three Years is the Trend in VaccinationsApril 2, 2015Originally published in the March 2015 issue of Veterinary Practice News After speaking with hundreds of practicing veterinarians over the past two years about vaccines and vaccination protocols, Richard Ford, DVM, has found that practitioners are slowly trending away from all vaccines to all pets every year. “I believe it is fair to say that some trends are emerging,” said Dr. Ford, a co-author on both the American Animal Hospital Association canine vaccination task force and the American Association of Feline Practitioners feline vaccination advisory panel. He has noted a growing the tendency to incorporate triennial boosters for core vaccines in dogs (distemper, parvovirus, adenovirus-2) and cats (panleukopenia, herpesvirus, calicivirus). “In speaking with vaccine sales representatives from around the country, I would estimate about half of the practices today routinely incorporate the three-year recommendation for core vaccines,” Ford said. Ford sees this largely as a good thing. “The science is abundantly clear on this point,” Ford said. “While some vaccines must be administered annually to sustain a reasonable level of protective immunity, others – namely the core vaccines – provide years of protective immunity in the majority of dogs/cats that are vaccinated. There is simply no medical …
Reminder: Keep Chocolate Away From DogsMarch 27, 2015The British Veterinary Association today warned about chocolate poisoning in pets, noting that 54 percent of U.K. veterinarians treated such cases over the Easter holiday last year. Chocolate consumption is more likely in dogs because of their tendency to eat just about anything. Chocolate contains theobromine, a chemical found in cocoa beans that dogs and other animals have a difficult time excreting, BVA stated. Just one ounce of milk chocolate per pound of body weight is enough to kill a dog, according to The Merck Veterinary Manual. Dark chocolate and cocoa powder are even most toxic, BVA stated. “It’s worth remembering that dogs in particular have a keen sense of smell and will easily win at any Easter egg hunt,” said BVA President John Blackwell, BVSc, MRCVS. “So wherever chocolate is being stored over Easter—inside or outside—make sure it is pet proof and stored out of reach of inquisitive and determined noses and paws to avoid an emergency trip to the vet at Easter.” The survey of 1,208 veterinarians discovered that 46 percent had no chocolate-related cases last Easter but that 18 percent had one patient, 26 percent had two or three, and 10 percent had at least four. …
Canine Cancer Lab TVAX Gets $2 MillionMarch 26, 2015Investors have put a lot of faith and money in TVAX Animal Health, a year-old company that is working on a T-cell-based cancer treatment for dogs. The Lenexa, Kan., subsidiary of TVAX Biomedical Inc. announced today that it closed on an additional $2 million in funding, adding to a stockpile that last summer totaled $12 million. “There are more than 3 million dogs treated for cancer each year, yet the available treatment options are limited,” CEO Tammie Wahaus said. “TVAX Animal Health strives to bring effective cancer treatment options to the U.S. veterinary market, and this round of financing will help us achieve this.” The cash infusion will fund a clinical trial of TVAX’s proprietary immunotherapy, which is designed to use a patient’s immune system to generate cancer-killing T-cells. The developer is focused on canine cancer but sees a potential market for the technology with cats and horses. The immunotherapy has the U.S. Department of Agriculture’s authorization. Among TVAX’s early investors were the Mid-America Angels network and the Kansas Biosciences Authority, both of which contributed to the new round of funding along with other parties. “We look forward to working with the TVAX management team to assist in …
Heart Drug Effective in Canine MMVDMarch 25, 2015An international clinical trial involving the drug pimobendan showed such positive results in canine heart patients that the researchers ended their work early, Texas A&M University reported Tuesday. The full study, which is sponsored by Boehringer Ingelheim Vetmedica, the maker of Vetmedin (pimobendan) chewable tablets, is expected to be published later. The research team, which included Texas A&M associate professor Sonya Gordon, DVM, Dipl. ACVIM, conducted what the university called the largest clinical study ever involving dogs suffering from myxomatous mitral valve disease (MMVD). A group of 360 canine patients was randomly split between those given pimobendan or a placebo in a double-blind study. Sixteen of the dogs were managed at Texas A&M, while the others were seen at 35 other trial centers in the United States and abroad. Pimobendan was found to delay the onset of clinical signs of congestive heart failure in dogs with increased heart size secondary to preclinical MMVD. “A midstudy analysis in mid-February 2015 indicated that pimobendan is clearly beneficial and did not raise any concern over the administration of pimobendan,” Texas A&M stated. “Based on these results the interim analysis committee recommended that the study be stopped and the lead investigators … …
3,000 Goldens Enrolled in Lifetime StudyMarch 24, 2015A suburban Chicago golden retriever will go down in history for her role in a ground-breaking study. Morris Animal Foundation announced today that young Chloe has enrolled as the 3,000th dog in the Golden Retriever Lifetime Study, a years-long research project that aims to better understand canine diseases. The Denver-based foundation called the longitudinal study the first of its kind in the veterinary world. “We are extraordinarily grateful not only to the thousands of owners who enrolled their dogs in this study but also to the many veterinarians who are on the front lines helping us gather data,” said David Haworth, DVM, Ph.D., the president and CEO of Morris Animal Foundation. “Of course, the real heroes are all the beautiful golden retrievers we will be following throughout their lives.” Chloe’s owner, Meredith Walters of Riverside, Ill., didn’t hesitate to offer up her pup, especially since her golden retriever Amber died from cancer and Cushing’s disease at age 13. “My hope is that this study will uncover data that will lead to information on why golden retrievers in particular are susceptible to cancer,” Walters said. “I knew that by enrolling Chloe I could honor Amber’s memory in a tangible …
What You Need to Know About Jaw LockingMarch 13, 2015Originally published in the February 2015 issue of Veterinary Practice News Last month, we discussed differential diagnoses for cats that are unable to close their mouths. One possible cause for cats’ and dogs’ inability to close the mouth is open-mouth jaw locking, which is rare enough that you may not have learned of it in veterinary school. Photo © 2012, John R. Lewis, University of Pennsylvania Figure 1: Open-mouth jaw locking in a Persian cat. Note the mouth is locked open so wide that there is no contact between maxillary and mandibular teeth. The slight shift of the mandible to the right suggests locking is occurring on the right. Clinical Signs and Etiology In cases of open-mouth jaw locking (OMJL), cats and dogs present with the mouth wide open, and the lower jaw often has shifted to the side where the coronoid process (the tip of the ramus) is locking on the ventrolateral aspect of the zygomatic arch (Figure 1). On presentation, patients may be drooling, pawing at the face and vocalizing. The defining clinical trait that allows OMJL to be distinguished from other possible causes of inability to close the mouth on conscious examination is that …
Purina: ‘No Quality Issues With Beneful’February 26, 2015Pet food manufacturer Nestlé Purina PetCare Co. is defending its Beneful brand as safe in light of a lawsuit that claims the food killed or sickened an undetermined number of dogs. The lawsuit alleges that the illnesses and deaths were linked to contaminated grain and food-grade propylene glycol used in eight Beneful kibble recipes. The document, filed Feb. 5 in U.S. District Court in San Francisco, requests class-action status, which if granted could turn thousands of dog owners nationwide into plaintiffs. St. Louis-based Purina issued a statement calling Beneful “a favorite of millions of pet owners and their dogs.” “First and foremost, there are no quality issues with Beneful,” the company stated. “Beneful is a high-quality, nutritious food enjoyed by millions of dogs every day. In fact, in 2014, nearly 1.5 billion Beneful meals were served to millions of happy, healthy dogs who enjoy and thrive on this food.” The lawsuit was filed by Discovery Bay, Calif., dog owner Frank Lucido, who said his German shepherd and Labrador retriever became sick and his English bulldog died within weeks of starting a Beneful diet. Lucido’s attorney, Jeffrey B. Cereghino, claimed in the lawsuit that testing of Beneful by the Association for Truth …
AKC Updates Website, LogoFebruary 25, 2015Staying current with technology, the 130-year-old American Kennel Club has launched a redesigned website along with what the registrar of purebred dogs describes as a streamlined, modern logo. The New York-based AKC contracted with the design firm Makeable to plan and build the new website, which is optimized for mobile devices and features greater functionality on all breed pages, the organization reported. “We spent more than a year immersed in research and discovery to ensure we presented a redesigned platform that would not only serve the members of our sport, but also the millions of dog owners around the country,” said AKC President and CEO Dennis Sprung. He called the website—www.AKC.org—“progressive and inclusive while also staying true to our heritage.” Besides maintaining an expansive log of purebred dogs, AKC advocates for canine health, oversees more than 5,000 clubs and affiliated organizations, and maintains rules and regulations governing competitions such as breed shows and agility events.