Study: Cancer Patients Benefit From Therapy DogsJanuary 14, 2015Therapy dogs lifted the spirits of adult cancer patients by improving their emotional well-being and quality of life, according to research co-sponsored by veterinary drug manufacturer Zoetis Inc. The clinical study, published this week in the Journal of Community and Supportive Oncology, involved patients receiving combined chemotherapy and radiation therapy for gastrointestinal, head or neck cancers. A questionnaire called the FACT-G (Functional Assessment of Cancer Therapy—General) found that the patients’ emotional well-being jumped over the course of animal-assisted visits even as they underwent “marked and significant declines in both physical and functional well-being,” according to the researchers. Principal investigator Stewart B. Fleishman, M.D., of New York’s Mount Sinai Beth Israel hospital called the work “the first such definitive study in cancer.” “Having an animal-assisted visit significantly improved [the patients’] quality of life and humanized a high-tech treatment,” Fleishman said. “Patients said they would have stopped their treatments before completion except for the presence of the certified Good Dog Foundation therapy dog and volunteer handler.” Besides Zoetis, the New York-based Good Dog Foundation and the Pfizer Foundation contributed to the research. “There is mounting evidence in human and veterinary medicine that the emotional bond between people and companion animals can …
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Dogs Can’t Hide Feelings From ScientistsJanuary 13, 2015Research conducted by Nestlé Purina PetCare Co. has confirmed that dogs, like people, become flush with happiness and excitement. The findings, according to Purina behavior scientist Ragen T.S. McGowan, Ph.D., illustrate how the human-animal bond works both ways, lighting up the lives of both people and pets. “Scientists have known for years how to evaluate negative states such as stress and anxiety in animals,” McGowan said. “Less is known about how to measure positive states such as happiness or excitement.” McGowan and her team used thermal, or infrared, cameras to examine how external stimuli can generate joyful emotions in dogs, the company reported today. The cameras measured temperature fluctuations in dogs’ eyes, ears and paw pads as blood flowed to those areas. “Thermal imaging has been widely used in animal welfare studies to assess inflammation in racehorses, for example, or to see how certain conditions affect livestock’s stress levels,” McGowan said. “This is one of the first times it is being used to measure positive responses in pets.” Part of the study involved having people with no connection to a group of shelter dogs sit with and pet them for 15 minutes, the company stated. The dogs …
Sleepypod Offers to Replace Crash-Damaged Travel GearDecember 23, 2014Sleepypod, whose dog travel harnesses have won top marks, is offering a free replacement or discounted pricing when a pet carrier or safety harness is damaged in a traffic accident. The program extends to competitors’ equipment as well. The burden of proof falls on pet owners, who must provide a police report and photos and answer a questionnaire. Damaged Sleepypod products are eligible for no-charge replacement—other than shipping costs—while owners of other brands may receive 30 percent off the Pasadena, Calif., company’s selection of mobile pet beds, carriers and harnesses. “Sleepypod wants to ensure pet safety after an auto accident,” said co-founder and lead product designer Michael Leung. “The integrity of a pet safety restraint may be compromised during an auto accident, so it is critical to inspect a pet carrier or harness for damage before being reused.” Damage may include anything from broken stitches and zippers to torn webbing. “If the accident is severe enough, webbing could be stretched, and therefore weaken the material,” Leung said. More information about the replacement program, which was announced Dec. 18, is available at www.sleepypod.com/accident-replacement-program. The nonprofit Center for Pet Safety, which conducts crash-testing, has deemed Sleepypod’s Clickit Sport …
Jaguar Seeks Limited Approval of Canine Diarrhea DrugDecember 22, 2014The startup drug company Jaguar Animal Health today reported the filing of its first New Animal Drug Application (NADA) with the U.S. Food and Drug Administration. If approved, the drug Canalevia would be used to treat dogs stricken with watery diarrhea during chemotherapy. Jaguar described Canalevia as a first-in-class anti-secretory agent intended for use in multiple animal species. The NADA filing requests Minor Use/Minor Species (MUMS) status for dogs as the drug undergoes further study. The limited designation would allow Jaguar to distribute Canalevia “before collecting all necessary effectiveness data, but after proving the drug is safe and showing that there is a reasonable expectation of effectiveness,” the San Francisco company stated. The decision to pursue MUMS status followed a meeting Oct. 22 between Jaguar and FDA representatives, according to the company. “[The] approach … will allow us to bring this new tool for management of certain chemotherapy side effects to dogs in need as soon as possible,” Jaguar reported. Canalevia contains crofelemer, an antidiarrheal found in the Croton lechleri tree and used to treat HIV-associated diarrhea in people. Jaguar in September launched its first non-prescription product, Neonorm Calf, for the treatment of watery diarrhea, or scours, in …
Aratana Moves Ahead on 2 Canine DrugsDecember 19, 2014A drug being studied for the treatment of osteoarthritis pain in dogs showed positive results in a pivotal field study, according to the developer, Aratana Therapeutics Inc. The Kansas City, Kan., veterinary drug maker also announced the launch of a pivotal field effectiveness study for a drug formulated to treat post-surgical pain in dogs. The osteoarthritis drug, code-named AT-001, was used in a blinded, placebo-controlled, multicenter dose-ranging study involving 280 client-owned dogs. The dogs, all of whom had osteoarthritis, were split into AT-001 and placebo groups and received daily oral doses for 28 days, Aratana reported Thursday. Validated owner-assessed pain scores showed that AT-001, which uses the compound grapiprant to target the EP4 receptor, demonstrated statistically significant improvements compared with the placebo, Aratana noted. The company expects to win U.S. Food and Drug Administration approval of AT-001 in 2016. “We believe AT-001 has the potential to be an important product in the well-established pain market,” said President and CEO Steven St. Peter, MD. Aratana also reported the initiation of a pivotal field effectiveness study of a drug licensed from Pacira Pharmaceuticals Inc. of Parsippany, N.J. AT-003 is an injectable, extended-release bupivacaine formulated for post-operative pain in dogs. A …
AKC Foundation Honors 6 Research FundraisersDecember 15, 2014Six organizations that over the past 20 years combined to donate more than $3.3 million to the American Kennel Club’s Canine Health Foundation have been named Distinguished Research Partners. Recognized Dec. 11 during the foundation’s Canine & Cocktails event in Orlando, Fla., were the Orthopedic Foundation for Animals, the Irish Setter Club of America Foundation, the Newfoundland Club of America Charitable Trust, the Collie Health Foundation, the Golden Retriever Foundation and the American Boxer Charitable Foundation. The amounts raised by the groups to assist with canine research ranged from the Irish Setter Club’s $131,100 to the American Boxer foundation’s $1,180,130. “These clubs and organizations are making a lasting impact on canine health,” said Shila Nordone, MS, Ph.D., the Canine Health Foundation’s chief scientific officer. “Their donations … are supporting research that addresses some of the most prominent health concerns for our dogs. We are tackling cancer, subaortic stenosis, hypothyroidism, degenerative myelopathy, epilepsy, bloat and cardiomyopathy. “Together, we are working to provide better treatments and more accurate diagnoses for all dogs.” The Canine Health Foundation, a grant-making institution, will celebrate its 20th anniversary in 2015. The foundation also honored Thomas A. Grabe, publisher of The Canine Chronicle, with …
$500,000 Dog Park Debuts in Prescott, Ariz.December 12, 2014What does $500,000 buy? In Prescott, Ariz., that amount of cash has given the community a renovated dog park done up in a firefighter theme. Prescott’s Willow Creek Dog Park was chosen for a half-million-dollar makeover a year ago when resident Linda Nichols won the annual Beneful Dream Dog Park Contest, a competition sponsored by pet food maker Nestlé Purina PetCare Co. Months of work were unveiled Wednesday as Nichols was joined by project managers Jason Cameron, host of the TV shows “Desperate Landscapes,” “Man Caves” and “Sledgehammer,” and pet expert Arden Moore. Nichols and more than 1,000 other dog owners nationwide entered the contest. Nichols’ winning entry was selected from among 14 finalists after a round of judging and public voting. Moore, whose task was to oversee the project from a dog’s point of view, helped bring to life Nichols’ wish for a firefighter theme. Today dogs can race around a miniature red fire truck, run though giant fire truck tires, rest in a covered firehouse lounge and cool off next to fire hydrant misters. The makeover fixed what Nichols described in her contest video as a “large, fenced dirt field with lots of weeds.” Prescott …
Canine Breed-Specific Considerations for AnesthesiaDecember 8, 2014Originally published in the August 2014 issue of Veterinary Practice News The practice of mating individuals with desirable physical characteristics and/or the ability to excel at performing specific tasks has led to the development of over 170 recognized dog breeds in the United States.1 This large variety of dog breeds translates to a very diverse patient population for veterinarians; one may have to anesthetize a great Dane and Chihuahua in the same day. Owners and dog breeders will often express concern about their particular breeds being sensitive to anesthesia; however, there is only one breed–specific anesthetic sensitivity that is supported by scientific evidence: greyhounds. Even though a particular breed may not have a true anesthetic sensitivity, that breed may still warrant specific anesthetic considerations. By selecting for specific traits in dogs we have inadvertently or purposely created unique anatomic, physiologic and metabolic characteristics that may ultimately affect how a given dog is able respond to general anesthesia. An excellent example of this is English bulldog. Shutterstock Greyhounds (and other sighthounds?) Sensitive to thiopental Prolonged recovery from propofol and other drugs The greyhound is the only breed with a documented breed-specific sensitivity to particular anesthetic drugs. Greyhounds have prolonged …
N.J. Hospital Provides Free Care to Military K9sNovember 18, 2014Four-legged military veterans are eligible for free specialty veterinary care under a partnership established between a New Jersey hospital chain, the American Humane Association and the United States War Dogs Association. The arrangement, announced Nov. 11 in honor of Veterans Day, recognizes the dogs’ months or years of service overseas on behalf of the U.S. military. Red Bank Veterinary Hospital, which has five New Jersey locations, will provide free specialty care to retired military working dogs and contract working dogs. The latter group is made up of canines supplied to the military by contractors. “For more than 25 years, Red Bank Veterinary Hospital has been a leader in providing veterinary care to the animals of New Jersey, but we now want to be known as the leader in veterinary care for our veteran dogs,” said hospital co-founder Anthony DeCarlo, VMD. The sponsors estimated that each dog saved the lives of up to 200 soldiers by uncovering bombs and weapons caches while working in war zones such as Iraq and Afghanistan. “Dogs are as essential to the military as humans, but unlike humans, these dogs are not guaranteed medical care following their retirement,” said Ron Aiello, president of the War …
Researchers Hope to Lick Canine Gum DiseaseNovember 17, 2014The American Kennel Club’s Canine Health Foundation has awarded more than $25,000 for studies of two potential solutions to periodontal disease in dogs. Paola Massari, Ph.D., of Boston Medical Center will investigate a vaccine that would use a dog’s immune system to fight the bacteria responsible for gum disorders leading to tooth loss and pain. Django Martel, DVM, of the Animal Medical Center in New York will work with colleagues to determine whether antibiotic gel therapy can reduce periodontal disease, the Raleigh, N.C.-based foundation reported. Periodontal disease is a common condition in adult dogs. Most canines show evidence of periodontal disease and associated discomfort by age 3, the foundation noted. “Just like … in humans, periodontal disease in dogs is a painful condition that profoundly affects quality of life and can lead to a multitude of health problems,” said the foundation’s chief scientific officer, Shila Nordone, MS, Ph.D. “We have strategically funded research that will have immediate impact by supporting the evidence-based use of antibiotic gels to treat progressive disease, while also funding research that will provide a long-term solution by developing an effective vaccine to prevent the disease from occurring in the first place,” she said. Each …
