footnotes

When Herbs And Surgery Don’t Mix

Failing to ask clients about any herbs their pet has received before surgery could lead to bleeding disasters during surgery.  Specifically, botanicals that interfere with clotting could transform an otherwise routine surgery into a frustrating and lengthy exercise.1   False Sense of Security While the true clinical impact remains clouded by lack of controlled research in both veterinary and human patients,2  this paucity of safety information may be creating a self-perpetuating cycle of false-negative information.3   The unregulated and untested nature of veterinary plant-based products amplifies uncertainties over product strength, potential misidentification, adulteration and species-specific or idiosyncratic variations in drug metabolism or effects.4 In particular, products with a multiplicity of ingredients, such as Chinese herbal formulations, especially when administered chronically, exhibit a disproportionately greater percentage and severity of side effects, compared to single-herb supplements.5,6,7    Harmful drug-herb interactions involving mixtures of herbs heighten the hurdles of identifying the source of the interaction. Mechanisms by which herbs may influence bleeding include direct pharmacologic actions and indirect interactions.8   Indirect (namely, herb-drug) interactions involve either pharmacodynamic or pharmacokinetic influences. Antiplatelet Effects   From top to botton, garic, ginger, ginko and ginseng. Veterinary …

CoQ10 Shows Promise For Hearts

FOOTNOTES 1. Freeman LM and Rush JE.  Nutrition and cardiomyopathy:  lessons from spontaneous animal models.  Curr Heart Fail Rep.  2007;4(2):84-90. 2. Hamlin RL and Buffington CAT.  Nutrition and the heart.  Veterinary Clinics of North America:  Small Animal Practice.  1989;19(3):527-538. 3. Freeman LM.  Interventional nutrition for cardiac disease.  Clinical Techniques in Small Animal Practice.  1998;13(4):232-237. 4. Rocha M and Victor VM.  Targeting antioxidants to mitochondria and cardiovascular diseases:  the effects of mitoquinone.  Med Sci Monit.  2007;13(7):RA132-RA145. 5. Bolcal CC, Yildirim V, Doganci S, et al.  Do N-acetylcystein, ß-glucan, and coenzyme Q10 mollify myocardial ischemia-reperfusion injury?  The Heart Surgery Forum.  2007;10(3):E222-E227. 6. Bolcal CC, Yildirim V, Doganci S, et al.  Do N-acetylcystein, ß-glucan, and coenzyme Q10 mollify myocardial ischemia-reperfusion injury?  The Heart Surgery Forum.  2007;10(3):E222-E227. 7. Haas RH.  The evidence basis for coenzyme Q therapy in oxidative phosphorylation disease.  Mitochondrion.  2007;7S:S136-S145. 8. Haas RH.  The evidence basis for coenzyme Q therapy in oxidative phosphorylation disease.  Mitochondrion.  2007;7S:S136-S145. 9. Bolcal CC, Yildirim V, Doganci S, et al.  Do N-acetylcystein, ß-glucan, and coenzyme Q10 mollify myocardial ischemia-reperfusion injury?  The Heart Surgery Forum.  2007;10(3):E222-E227. 10. Pepe S, Marasco SF, Haas SJ, et al.  Coenzyme Q10 …

Acupuncture For Bone Cancer Pain

1. Thoresen A.  Acupuncture and cancer therapy.  Obtained at http://home.online.no/~arethore/engelsk/foredrag/kreft.html on 05-26-08. 2. Thoresen A.  Small animal cancer.  Obtained at http://med-vetacupuncture.org/english/articles/an-canc.html on 05-26-08. 3. Kaphle K, Wu Y-L, and Lin JH.  Thirtieth Annual Congress on Veterinary Acupuncture:  IVAS Report.  eCAM.  2005;2(2):239-242. 4. Chi Institute of Chinese Medicine.  TCVM News.  Issue 4.  September 3, 2004.  P. 6. 5. Flaim D.  Worth their weight in gold.  Animal House.  July 16, 2002.  Obtained at Newday .com at http://64.233.167.104/search?q=cache:_jWqyEXHYOYJ:www.newsday.com/entertainment/nyc-pets-implants,0,918948.column+gold+beads+cancer+durkes&hl=en&ct=clnk&cd=2&gl=us on 05-26-08. 6. Dvorak RF.  Permanent acupuncture with gold bead implants.  Obtained at http://www.himmlisch.com/goldbeads.htm on 05-26-08. 7. Repeated personal experience and personal communication with other veterinary acupuncturists, 1997-2008. 8. Buridan’s ass.  Defined at http://www.encyclopedia.com/doc/1O87-Buridansass.html. 9. Wesa K, Gubili J, and Cassileth B.  Integrative oncology:  complementary therapies for cancer survivors.  Hematol Oncol Clin North Am.  2008;22(2):343-353, viii. 10. TCM Local Applications for Cancer Pain Management.  Obtained at http://www.shen-nong.com/eng/exam/specialties_cancer2pain.html on 05-27-08. 11. Sabino MAC and Mantyh PW.  Pathophysiology of bone cancer pain.  Supportive Oncology.  2005;3(1):15-24. 12. Sabino MAC and Mantyh PW.  Pathophysiology of bone cancer pain.  Supportive Oncology.  2005;3(1):15-24. 13. Sabino MAC and Mantyh PW.  Pathophysiology of bone cancer pain.  …