The future of canine cancer treatmentMarch 15, 2022The use of immunotherapies to treat cancers has become increasingly widespread in human medicine, with some of these promising therapeutics producing remarkable outcomes.
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The race to develop immunotherapies for canine lymphoma and osteosarcomaJanuary 2, 2019There are many reasons why development of immunotherapies in dogs has been slow. Although cancer, and in particular lymphoma and osteosarcoma, is frequent in dogs, just one percent of owners have pet insurance; those who don’t are willing to spend only a limited amount of money to treat their dog, especially when initial treatment results are not as dramatic as in humans.
MAF awards Penn $775K to test osteosarcoma immunotherapy vaccine in dogsApril 20, 2018Morris Animal Foundation (MAF) has awarded a $775,000 grant to the University of Pennsylvania to test a vaccine that could improve longevity and quality of life for dogs with osteosarcoma. The research team will conduct clinical trials to evaluate a novel immunotherapy treatment that combines a molecule expressed by cancer cells with a modified live form of Listeria monocytogenes. A pilot study demonstrated this combination elicited a powerful, targeted immune response directed against osteosarcoma cells in patients suffering from this type of cancer. "This could be an incredible breakthrough in the fight against osteosarcoma, a highly aggressive and deadly cancer," said Kelly Diehl, DVM, DACVIM (SAIM), senior scientific programs and communications adviser at MAF. "For the last 50 years, Morris Animal Foundation has been funding cancer studies, and this is one of the largest, single grants we have ever awarded. The results of the pilot study were so compelling, that we knew we had to support this research team and their progression to a clinical trial." The vaccine, created by removing harmful genes from the Listeria bacteria and then attaching markers of osteosarcoma cells, supplements standard osteosarcoma treatment of amputation and chemotherapy by attacking cancer cells that …
The latest in treating canine lymphomaJune 26, 2017Everybody reading this article has likely had their life touched by cancer, either personally or through a friend, family member or beloved pet. Cancer is something we all want eradicated.
Immunotherapy: The next best hope for defeating cancer?December 21, 2016Whether you’re treating something as deadly as cancer or as frustrating as chronic allergies, immunotherapy offers the possibility of slowing or reversing disease.
