Canadian researchers team up to fight canine osteosarcomaJune 14, 2018A group of researchers called the Dog Osteosarcoma Group–Biomarkers of Neoplasia (DOGBONe) at the University of Guelph in Ontario, Canada, have joined forces to determine more accurate ways of measuring bone cancer, with the main objective of identifying biomarkers to assess patients with canine osteosarcoma. The presentation of osteosarcoma in dogs is remarkably similar to that of humans, according to the Ontario Veterinary College (OVC); so much so that computers are unable to distinguish between tumor samples from each species based on gene expression patterns. These similarities make canine osteosarcoma research all the more valuable, as any progress in developing better treatments for one species means progress for the other as well. "The dogs are a model for the worst of the human disease," said Geoffrey A. Wood, DVM, Ph.D., DVSc (pathology), of the OVC's Department of Pathobiology. "Right now, the information we find out in human osteosarcoma serves as a model for the dogs. There's an opportunity to go both ways between the species, for the benefit of both." The team consists of the university's top osteosarcoma researchers from across four departments at OVC, including co-leaders Dr. Wood and Alicia Viloria-Petit, Ph.D., MSc, BSc, of the Department of …
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