Why do some greyhounds bleed and others clot excessively?

Deciphering the hemostatic teeter-totter

Sighthounds in general, and greyhounds in particular, have evolved over the past 6,000 to 7,000 years to follow their prey by sight. Hence, they have developed numerous physiologic and hematologic adaptations specific to the breeds.1

In retired racing greyhounds (RRGs), the packed cell volume (PCV), hemoglobin concentration, red blood cell (RBC) count, and whole blood viscosity are higher, while the white blood cell count, neutrophil count, and platelet count are lower than in other dogs (reviewed in 2). The serum total protein, globulin, alpha-globulin, and beta-globulin concentrations are also lower than in non-greyhound dogs.3-5 Interestingly, platelet aggregation under high shear, as determined with the platelet function analyzer 100...


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