Bigstock The U.S. Food and Drug Administration (FDA) has issued an Emergency Use Authorization (EUA) for generic Nitenpyram Tablets (nitenpyram) for the treatment of New World screwworm (NWS) infestations, or myiasis, in dogs, puppies, cats, and kittens. The authorization reportedly marks the first generic animal drug cleared for emergency use against NWS. The over-the-counter tablets are indicated for pets at least four weeks of age and weighing 2 lb. or more. Available in 11.4 mg and 57 mg strengths, dosing is based on the animal’s body weight. According to the FDA, nitenpyram acts rapidly against NWS larvae, killing most larvae within hours of the initial dose. Pet owners are advised to administer a second dose six hours after the first treatment to improve efficacy. However, because the drug’s effects are short-lived, it does not prevent future infestations or protect against reinfestation. The agency notes animals treated with nitenpyram may still require veterinary attention. A veterinary professional may need to remove any remaining live or dead larvae from affected wounds to reduce the risk of infection and minimize additional tissue damage. Veterinarians should also provide guidance on wound management and strategies to prevent reinfestation. The agency notes its decision was based on the available scientific evidence indicating nitenpyram may be effective for treating NWS myiasis in certain dogs and cats and that the product’s potential benefits outweigh its known and potential risks. The authorization expands access to an additional treatment option as officials continue efforts to contain and eradicate NWS. Nitenpyram Tablets contain the same active ingredient as the brand-name product, Capstar (nitenpyram), which was originally approved in 2000 for the treatment of flea infestations. The FDA determined the generic tablets are bioequivalent to the reference product.
