Pets' influence on youth development to be exploredSeptember 27, 2019The role of pet ownership in predicting trajectories of youth development is set to be explored in an upcoming Tufts University research study.
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Tufts veterinarians treat canine cancer with experimental drugJanuary 18, 2018When Edward Sloan's dog, Dozer, a 7-year-old bull mastiff went blind seemingly overnight, a devastating diagnosis revealed Dozer had cancer. Desperate to save his best friend, Sloan found a clinical trial at the Cummings School of Veterinary Medicine at Tufts University, where Abbey Sadowski, DVM, found that Dozer had "lost a lot of weight [and] had several weeks of history before he even saw us." Dr. Sadowski and Cheryl London, DVM, Ph.D., are testing an experimental drug—called KPT-9274—combined with just one round of chemotherapy to treat lymphoma. "We had this remarkable response … when you combine these two things together you can get a dramatic reduction in disease," Dr. London said. Early results of the small study have been promising, especially for Sloan and Dozer. "A single heroic dose … the next day he was able to see," Sloan said. Dozer is three months in remission, and his medical reversal of fortune could eventually lead to a breakthrough in human medicine. London said the outcome of a canine trial is a valuable piece of the research puzzle. "The benefits to the human side are that you get a drug into humans that's actually much …
Hydrocephalic fur seal undergoes brain surgery at TuftsDecember 28, 2017A neurosurgical team at Cummings School of Veterinary Medicine at Tufts University has successfully performed a first-of-its-kind brain surgery on a female adult Northern fur seal in an attempt to address her worsening neurologic condition. Ziggy Star is recovering well at her permanent home at Mystic Aquarium in Mystic, Conn. Ziggy was first seen at the Henry and Lois Foster Hospital for Small Animals at Cummings Veterinary Medical Center at Tufts University in September for a progressive condition that was causing severe neurologic episodes, difficulty moving, reduced training response, and cluster seizures. An MRI revealed an accumulation of cerebral spinal fluid in the brain—hydrocephalus. Mystic Aquarium took in Ziggy approximately four years ago after she was found stranded on the California coast and deemed non-releasable by the federal government. At the time, she had an MRI that showed some neurologic abnormalities. She received treatment, but her symptoms continued to progress at a concerning rate, with the seizures emerging more recently. "The MRI taken recently by our team showed that the brain was disappearing due to the excess fluid, and it was significantly worse than the last study four years ago," said Ane Uriarte, DVM, Diplomate of the European College of …
Tufts researchers find first genomic biomarkers in extracellular vesiclesJuly 27, 2017Important biomarkers have been found in extracellular vesicles in dogs with myxomatous mitral valve disease (MMVD) and congestive heart failure, according to researchers at Cummings School of Veterinary Medicine at Tufts University in Grafton, Mass.
