MAF study finds tramadol ineffective against osteoarthritis in dogsMay 9, 2018 A report funded by the Morris Animal Foundation (MAF) out of the University of Georgia has found tramadol to be ineffective in alleviating signs of pain associated with osteoarthritis in dogs. "The data shows conclusively that tramadol is not an effective drug in treating the pain associated with arthritis in the dog, despite its common recommendation," said Steven Budsberg, DVM, BS, MS, DACVS, professor of surgery/director of clinical research at the University of Georgia College of Veterinary Medicine. "This use of tramadol is a classic example of failing to acknowledge and control for bias when evaluating a potential treatment." The reported data was collected by Dr. Budsberg and his research team via a randomized, blinded, placebo, and positive-controlled crossover study. The group compared tramadol against both placebo and nonsteroidal anti-inflammatory drugs, with dogs afflicted with osteoarthritis of the elbow or knee assigned to receive each of three treatments in a random order and each treatment arm lasting for 10 days. Improvement was measured using a variety of tests to evaluate the patient's gait and pain. The results showed no improvement when tramadol was administered compared to either baseline or placebo. "This study reinforces the need to carefully and …
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ACVIM Foundation dissolves, gives funds to MAFJanuary 4, 2018 The American College of Veterinary Internal Medicine (ACVIM) Foundation, as part of its planned dissolution, has selected Morris Animal Foundation (MAF) to receive its remaining funds to invest in animal health research. "We believe that partnering with Morris Animal Foundation is the best way to see execution on the ACVIM Foundation's mission," said Linda Fineman, DVM, DACVIM, president of the ACVIM Foundation. "Through a named fund at Morris Animal Foundation, we will continue to improve the health of animals worldwide." The ACVIM board of regents previously voted to dissolve the ACVIM Foundation on a recommendation from the foundation's board of directors. A transition task force was created to oversee distribution of remaining funds. Morris Animal Foundation has established the ACVIM Fund, while the ACVIM plans to support MAF by sharing MAF research findings with veterinary audiences. "We look forward to working collaboratively with ACVIM to use these funds in a manner that will best advance veterinary medicine and improve animal health and well-being," said John Reddington, DVM, Ph.D., president and CEO of MAF. The ACVIM Foundation has distributed remaining funds totaling nearly $424,000 to MAF. Grants awarded with these funds will recognize …
MAF explores study diversity, applications to animal healthSeptember 18, 2017According to a new research paper from the Morris Animal Foundation (MAF), determining what type of research study to do, and when, are key decisions scientists must make when embarking on a new project. In an editorial published Sept. 11, 2017, in the International Animal Health Journal, "Epidemiology and its Application to Animal Health," Missy Simpson, DVM, intramural research scientist and epidemiologist with MAF, provides guidance on study types for veterinary researchers and animal health scientists. The editorial is an overview of study types, and highlights MAF's Golden Retriever Lifetime Study as an example of a cohort study, and also discusses advances in store for observational studies. "Health research is diverse and varied and covers a spectrum from basic research—which describes the early discovery and development phase—to applied research," said Dr. Simpson. "Each phase of research is essential to move scientific discovery forward and advance health." In the paper, Simpson discusses interventional research consisting of clinical trials, and observational research, including descriptive studies, case-series studies, case-control studies, and ecologic, retrospective, and longitudinal studies. "An advantage of performing clinical trials in animals is that health outcomes tend to be achieved on …
