VPN Plus+ ExclusiveCBD or CBD and THC combined?May 29, 2020While cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) are both phytocannabinoids derived from cannabis plants, differences in their chemical structures allow each to interact with unique receptors, resulting in distinct molecular targets and physiological effects. Namely, THC shows high affinity toward CB1 receptors, which are present in central and peripheral neurons, resulting in the euphoric effect commonly attributed to cannabis intoxication. In contrast, CBD does not bind CB1 at relevant concentrations and is nonintoxicating. Instead, CBD interacts, to various degrees, with other receptors (agonism at TRPV1 and 5-HT1A, antagonism at TNFα, GPR55, and GPR18), which may be relevant for its suggested therapeutic effects. Practical considerations Recently, CBD- and THC-containing products for people and pets have become more widely available, especially in jurisdictions that have passed legislation allowing the sale of such items intended for human use. Evolving regulatory frameworks and social perceptions have also renewed interest in the potential therapeutic properties of cannabinoids for animals. Importantly, there are no authorized veterinary drugs containing cannabinoids in the U.S., and any state laws permitting the use of medical cannabis do not apply to use in animals. Increasingly, the veterinary profession is being asked to weigh in on the potential roles of CBD and …
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Is a heartworm vaccine on the horizon?May 21, 2020Protecting dogs from deadly parasites and combating drug resistance to heartworm medications are the central goals behind a new Morris Animal Foundation-funded study.
Biopharma company partners to make oral COVID-19 vaccineMay 20, 2020A vaccination tablet for the novel coronavirus might soon be available, thanks to a new partnership between KindredBiosciences and Vaxart.
Report animal drug shortages ASAPMay 11, 2020FDA has issued guidance to ensure the availability of drug products during the novel coronavirus pandemic.
When clients question your pharmacy pricesMay 8, 2020When your team educates clients about the safety and benefits of buying pet medications from your hospital, you’ll win their trust, confidence, and loyalty.
Feline heartworm disease: A diagnostic dilemmaMay 7, 2020Heartworm disease is an elusive diagnosis in feline patients. As such, a thorough understanding of the pathogenesis of feline heartworm disease (FHWD) is needed to interpret test results.
Fecal microbiome testing: Is the research reliable to ensure a healthy pet?May 7, 2020While enthusiasm for new discoveries and hypotheses is a necessary part of scientific progress, the premature application of these to clinical patients can be harmful.
Generic equine sedative OKed by FDAMay 1, 2020Detomidine hydrochloride is used to manage pain in both mature horses and yearlings when undergoing minor surgical procedures, such as the repairing of skin lacerations, as well as diagnostics.
Digital imaging equipment—Show, don't tellApril 27, 2020Digital imaging can help better communicate health issues and treatment plans to pet owners. And when it comes to patients getting the care they need, shouldn’t you use every tool at your disposal?
Why proper instrument reprocessing mattersApril 27, 2020There are some areas of instrument sterilization that need to be addressed to ensure healthy outcomes in patients.
