Brain Teaser: Can you solve this puzzle?November 1, 2018 Presentation A patient is dysphoric when recovering from anesthesia. Challenge How do you diagnose dysphoria? What do you need to differentiate dysphoria from? How would you treat dysphoria? Check your answer on the next page.
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Brain Teaser: Can you solve this puzzle?October 17, 2018 Presentation Cystotomy in a five-year-old Rottweiler who had 178 struvite stones. Challenge What is the holding layer—the one to include in the suture line? Which suture material is ideal? Which needle is best? Which suture pattern is recommended? Check your answer on the next page.
VolitionRx tests nucleosome diagnostic for veterinary space applicationsOctober 5, 2018 VolitionRx Ltd., a multinational Belgium-based life sciences company with offices in Texas, London, and Singapore, announced it is entering the veterinary market after "very encouraging" preliminary results from a study using its NuQ diagnostic blood tests for canine cancer testing. NuQ, currently used to screen for colorectal and prostate cancers, works by measuring and analyzing irregular levels of nucleosomes—a section of DNA wrapped around a core of proteins—in the blood to identify cancers. According to the company, the proof-of-concept study showed that blood nucleosomes also can be detected in dogs. With the promise of veterinary medicine applications, VolitionRx said it will now move NuQ into larger trials to answer the question of whether the method will work with animals. The company said it intends to outsource much of the veterinary clinical trial work through a partnership with Heather Wilson-Robles, DVM, DACVIM, associate professor and Fred and Vola N. Palmer chair in comparative oncology with Texas A&M College of Veterinary Medicine & Biomedical Sciences in the Small Animal Clinical Sciences department. "The Texas A&M University College of Veterinary Medicine Oncology Department is excited for the opportunity to collaborate with Volition," said Dr. Wilson-Robles. "Its innovative work in …
Penn Vet doctors receive NIH grant to target canine autoimmune diseaseOctober 4, 2018Nicola J. Mason, BVetMed, PhD, and Aimee S. Payne, MD, PhD, have received the National Institutes of Health (NIH) Director's Transformative Research Award, part of the institute's High-Risk, High-Reward Research program, for their work in targeting autoimmune disease in dogs. Under the grant, Drs. Mason and Payne are looking to evaluate a genetically engineered cell-based therapy to treat dogs with naturally occurring autoimmune skin disease known as pemphigus. Dogs are one of the few other species to develop pemphigus, a condition that mirrors pemphigus in human patients. Evaluation of this approach to treat pet dogs with the disease may ultimately lead to breakthrough therapies for humans. According to the Autoimmune Disease Research Center at Johns Hopkins, at least 10 million Americans suffer from the more than 80 illnesses caused by autoimmunity. "The successful treatment of autoimmunity in the family dog using this unique approach would not only be a breakthrough in veterinary medicine, but could also change the way autoimmune disease is treated in humans," said Mason, associate professor of medicine and pathobiology at the School of Veterinary Medicine at Penn Vet. "We believe that this work may facilitate the translation of cellular immunotherapies for a broad range of canine …
FDA approves Boehringer Ingelheim's Semintra for feline hypertensionOctober 2, 2018The U.S. Food & Drug Administration has approved Semintra (telmisartan oral solution) 10 mg/mL oral solution for the control of systemic hypertension in cats, according to Boehringer Ingelheim. The product was designed specifically with cats in mind to provide safe, reliable, and convenient long-term control of blood pressure, said Boehringer Ingelheim. "We are proud to continue to set new standards of care for cats to optimize their health and well-being through the veterinarian," said Shawn Hooker, global head of Strategic Business Unit Pet Vet at Boehringer Ingelheim. "Early disease detection and early treatment are key to ensure cats live longer and happier lives. With Semintra, we offer a pet owner-friendly, easy-to-give solution to help raise the quality of life of cats with hypertension, while providing reliable long-term blood pressure control." Semintra is for oral use in cats only. The most common side effects reported in field studies include vomiting, diarrhea, lethargy, anemia, dehydration, poor appetite, and weight loss. It has not been evaluated in cats with systolic blood pressure > 200 mmHg, cats with hepatic disease, cats younger than 9 months of age, or cats that are pregnant, lactating, or intended for breeding. Visit semintra.com for …
Is cancer increasing in cats and dogs?October 2, 2018I often see claims in the media—from veterinarians as well as lay people—that canine and feline cancer rates are rising, and we are experiencing an “epidemic.” Usually, this is a prelude to further claims about the causes of this so-called epidemic. Finally, a solution is typically offered, involving either eschewing the purported causes of cancer or employing a diet, supplement, “detox” program, or some other product or method recommended (and sold) by whomever is making the claims.
IsoPet canine soft-tissue sarcoma treatment delivers 'complete response'September 28, 2018Vivos Inc., a pharmaceutical company that develops minimally invasive treatments to combat cancer in humans and animals, reported that its signature product, IsoPet, was used to treat a hind-leg soft-tissue sarcoma in a Shetland sheepdog at the University of Missouri Veterinary Health Center in Columbia, Mo. The treatment of the sarcoma resulted in a "complete response," meaning tumor destruction and disappearance, together with a healthy recovery, according to veterinary oncologist Charles Maitz, DVM, PhD, DACVR-RO. Results will be presented in at the Veterinary Cancer Society's annual conference in Louisville, Ky., Oct. 17 - 20. Post-treatment imaging and dosimetry provided confirmatory data addressing questions previously raised by U.S. Food and Drug Administration review panel, including: Near-uniform placement by injection and interstitial perfusion within the tumor without vascular clearance to normal organs and tissues Very high therapeutic ratios (radiation dose to the tumor relative to normal organs) Effective, highly localized, high-dose radiotherapy, and complete absence of adverse side-effects in critical normal tissues The University of Missouri is now advertising availability of IsoPet treatment for dogs and other species, including treatment of equine sarcoids. "The successful treatment of the cat and dog subjects thus far increases the likelihood of …
OVC veterinarian removes tumor, replaces dog's skull using 3D printingSeptember 27, 2018A veterinarian from Ontario Veterinary College (OVC) has replaced part of a dog’s skull with a 3D-printed titanium plate after removing a tumour that was weighing down her head.
Pad corns: A pain for both dog and veterinarianSeptember 26, 2018A canine corn is a focal circular area of hyperkeratinization found in the digital paw pads of sighthound breeds (e.g. greyhound, whippet, and lurcher). A prevalence of around five to six per cent in retired greyhounds has been reported in the literature (Lord et al, 2007), making it the most common dermatologic condition among this group of dogs. Approximately 80 per cent of corns occur in digits three and four, while 80 per cent are found in the digits of the thoracic limbs (Guilliard et al, 2010). Their occurrence has not been reported in the metacarpal and metatarsal paw pads. Corns commonly cause lameness, which can be severe. The lesion is analogous to heloma durum (corn/clavus), which usually occurs on the foot in humans (Roven, 1968).
Survey highlights impact of opioid shortages in veterinary medicineSeptember 17, 2018A nationwide survey conducted by Wedgewood Pharmacy aims to show the unintended consequences for veterinary medicine caused by the Drug Enforcement Administration's (DEA) efforts to address the national opioid crisis. To address the misuse and diversion of opioids by people, the DEA has proposed an average 10 percent decrease in the 2019 manufacturing quotas for six frequently abused opioids, including five key Class II opioid drugs commonly used by veterinarians. When supplies of these drugs are limited, manufacturers and distributors give preference to allocating supplies for use in human health, creating shortages for veterinary medical practitioners, Wedgewood said in a statement. Key survey findings: In 2017, anywhere from 27 to 73 percent of veterinary professionals have had difficulty obtaining necessary supplies of five opioids (hydromorphone, morphine, fentanyl, hydrocodone, and oxymorphone) they consider "important to your practice and to your patients' health" by 50 to 80 percent of respondents. Shortages of these opioids have led to the use of less effective, non-narcotic alternatives such as NSAIDS (83 percent), increased patient suffering (71 percent), use of a local anesthetic (49 percent), postponed procedures (26 percent), and patient deaths (3 percent) 88 percent of respondents "rarely" …
