VPN Plus+ ExclusiveIs immunotherapy the key to wiping out canine cancer?June 24, 2020An intact and functional immune system is essential to protect an organism against invading pathogens and infectious disease. However, the immune system also plays a pivotal role in identifying and eliminating transformed cells that, if left unchecked, would progress to cancer. Clinical evidence of the immune system's ability to control cancer comes from a number of observations in both the veterinary and medical settings. Consider the following examples: Cats receiving chronic immunosuppression following renal transplant have a higher incidence of lymphoma compared with the general feline population1,2 Spontaneous regression of transmissible venereal tumor is associated with an increased proportion of tumor-infiltrating cytotoxic CD8+ T cells3 Canine osteosarcoma patients that develop bacterial infections after limb-sparing surgery experience significantly prolonged survival times.4 The presence of tumor-specific, cytotoxic T cells within tumors, such as ovarian carcinoma, confers a favorable prognosis,5 whereas infiltration with regulatory or suppressor T cells confers a worse prognosis6 These observations, coupled with two decades of experimentation in murine cancer models, indicate that finding ways to initiate, augment, and broaden a patient's antitumor immune response holds promise for the treatment and possible prevention of cancer. Indeed, this is the aim of cancer immunotherapy, and recent advances in this field have …
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Hookworm rampant across U.S.June 24, 2020Des Moines, Iowa, is the number one city for hookworm in May, the Companion Animal Parasite Council (CAPC) reports.
Why do some greyhounds bleed and others clot excessively?June 24, 2020Sighthounds in general, and greyhounds in particular, have evolved over the past 6,000 to 7,000 years to follow their prey by sight. Hence, they have developed numerous physiologic and hematologic adaptations specific to the breeds.
Grain-free diet not linked to DCM in dogs, research review findsJune 22, 2020Dilated cardiomyopathy (DCM) in dogs is largely an inherited disease and not the result of a grain-free or legume-rich diet.
Canine ophthalmic emetic OKed by FDAJune 22, 2020The generic form of a dopamine agonist for inducing vomiting in canines has been approved by the U.S. Food and Drug Administration’s (FDA’s) Center for Veterinary Medicine.
Uniting human, animal pharma/biotech strengthens fight against cancerJune 8, 2020Using a One Health approach to enhance developments for human and canine cancer treatments is central to a new manuscript, supported by World Small Animal Veterinary Association (WSAVA’s) One Health Committee (WSAVA OHC).
Helping a dog age gracefully starts in youthJune 3, 2020We all want to help our patients enter the third act of life gracefully, but what exactly does that mean and how can it be achieved?
Blue-green algae: What it is and why it's so deadlyJune 3, 2020Although commonly referred to as blue-green “algae,” these organisms are not plants. Rather, they are bacteria—cyanobacteria, to be precise. And they are deadly to dogs, cats, and other animals.
New legislation ensures immunization of imported dogsMay 20, 2020Protecting America’s dogs and people from parasites and contagious disease is central to a new bipartisan bill introduced in the U.S. House of Representatives.
Canine heart disease test on the pulseMay 13, 2020A test allowing for the early detection of dilated cardiomyopathy (DCM) in dogs may soon be in the works, thanks to new joint venture by Hill’s Pet Nutrition and Embark.
