OSU enrolling dogs with mammary cancer for clinical trialAugust 29, 2018Oregon State University's Lois Bates Acheson Veterinary Teaching Hospital is now enrolling dogs with mammary cancer in a new clinical trial. Dog owners considering standard tumor removal surgery may be able to choose a new surgical procedure involving an intravenous injection of a cancer cell-illuminating nanoparticle compound that highlights exactly which tissue needs to be removed. After the mammary tumor is removed, the surrounding tissue is irradiated with an infrared laser that causes the nanoparticle compound to heat up, killing any remaining cancer cells. The compound, developed by researchers in the Oregon State University College of Pharmacy, has been found to effectively cure cancer in mice. The new procedure eventually may be most beneficial for treating tumors in challenging anatomic areas, such as the brain and spine, according to Milan Milovancev, DVM, DACVS-SA, an OSU associate professor of small animal surgery participating in the study. The Oregon State University Carlson College of Veterinary Medicine is a member of a national consortium of veterinary oncology centers, managed by the National Institutes of Health, with a focus on translational veterinary medicine. Owners who believe their pets may be good trial candidates can ask their veterinarian …
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Behavior basics for veterinary emergency clinicians and techniciansAugust 24, 2018Emergency and/or critical care workers are often faced with urgent cases and fast-paced environments. Unfortunately, this setting is not always conducive to caring for patients’ emotional needs. Here are some easy ways to help them feel more at ease in even the most trying situations.
New research for canine, human Type 1 diabetes holds promiseAugust 24, 2018Reversing Type 1 diabetes in dogs and humans without the use of daily insulin injections or pumps may become a reality, thanks to a collaboration between Purdue University and the Indiana University School of Medicine. In a preclinical study, researchers developed a mixture of collagen and pancreatic cells and engineered a delivery method that successfully reversed Type 1 diabetes within 24 hours and maintained insulin independence for 90 days. A clinical study in dogs with naturally occurring Type 1 diabetes in collaboration with Purdue's College of Veterinary Medicine is next. "We plan to account for differences from mouse to human by helping dogs first," said Clarissa Hernandez Stephens, first author on the work and a graduate researcher at Purdue's Weldon School of Biomedical Engineering. "This way, the dogs can inform us on how well the treatment might work in humans." Because diabetes in dogs and humans occurs the same, both potentially could benefit from the same cure: A new set of pancreatic cells to replace islets (clusters of cells) that aren't releasing insulin to monitor blood glucose levels. Islet transplantation isn't new, and it poses challenges: It requires multiple donors, it's invasive, and large numbers of transplanted …
NIH awards UF veterinarian five-year grant to study canine diabetesAugust 24, 2018Allison O'Kell, DVM, a small animal internal medicine specialist and clinical assistant professor at the University of Florida College of Veterinary Medicine, has received a Mentored Clinical Scientist Research Career Development Award from the National Institutes of Health in support of her studies relating to canine diabetes. The five-year grant, known as a K08, will support Dr. O'Kell's career and research project. "The overall goal of my research is to study the causes of diabetes in the dog," O'Kell said. "We hope that the work will benefit dogs with this disease, but also to help us better understand whether studying the disease in dogs may be a novel way to understand the disease in humans." The disease has been increasing in prevalence over time in both dogs and humans, emphasizing the importance of research to determine the underlying causes of the disease as well as methods for prevention and treatment, she added. O'Kell's primary mentor is Mark Atkinson, PhD, the American Diabetes Association Eminent Scholar for Diabetes Research and Jeffrey Keene Family Professor in the UF College of Medicine. Atkinson also directs the UF Diabetes Institute and has been investigating human Type 1 diabetes for …
The skinny on pet supplementsAugust 23, 2018While certain supplements can have a place in joint disease management, some veterinarians are concerned about how they might be perceived by pet owners.
Increasing geriatric pet visitsAugust 23, 2018In the first two parts of this series, I discussed the staggering number of geriatric pets not visiting their primary care clinic and offered suggestions to help families caring for these animals—but how do we go about getting these grey muzzles into door so that we can help them?
Blue Buffalo Co. launches canine obesity, joint health dietAugust 23, 2018Blue Buffalo Co. has launched BLUE Natural Veterinary Diet W+M Weight Management + Mobility Support for dogs. According to the company, the therapeutic diet contains L-carnitine, which has been shown to facilitate weight loss and help maintain lean body mass in dogs; betaine, which supports dogs' ability to metabolize fat; moderate levels of dietary fiber from powdered cellulose, pea fiber, dried tomato pomace, and chicory root, which promote satiety and weight loss; turmeric, vitamin C, and vitamin E to limit oxidative stress, which has been found to be involved in the pathogenesis of osteoarthritis. It also contains EPA, DHA, glucosamine, and chondroitin sulfate, as well as deboned salmon, fish oil, canola oil, flaxseed, and shrimp meal.
Confronting the obesity epidemicAugust 22, 2018Pet obesity is on the rise, although really, that probably isn’t a surprise to most veterinarians since the number of conference sessions, scientific studies, and therapeutic diets addressing this issue are increasing exponentially.
UC Davis veterinarian discovers rare blood disorder in catAugust 22, 2018Miao Miao, a four-year-old male domestic shorthair cat, was brought to the University of California, Davis veterinary hospital with persistent nosebleeds. Based on previous medical issues, his owners were aware that he had some variation of a blood platelet disorder, but the exact makeup of that was never discovered. Specialists with UC Davis' internal medicine service ran a range of tests to discover the root of his bleeding issue. A complete blood count showed that Miao Miao was not anemic, had no evidence of inflammation, and a normal platelet count. An ultrasound also was performed, which showed that Miao Miao had no evidence of bleeding into any of his other bodily cavities. Miao Miao was hospitalized for a few days to ensure he did not develop significant bleeding, and so that the team could discuss his case with other clinicians and researchers. Through a collaboration of UC Davis emergency, internal medicine, and research specialists, a unique cause to Miao Miao's bleeding was found. Ronald Li, DVM, MVetMed, PhD, DACVECC, a critical care specialist with the UC Davis veterinary hospital's emergency room, operates a platelet physiology laboratory with equipment and capabilities found in only a handful of veterinary centers around …
FDA approves NexGard expanded label claimsAugust 22, 2018Merial, part of Boehringer Ingelheim, received approval from the U.S Food and Drug Administration to expand the label claims for NexGard (afoxolaner). The flea and tick control product is now approved to prevent Borrelia burgdorferi infections as a direct result of it killing Ixodes scapularis vector ticks, commonly called black-legged, or deer, ticks. NexGard is the first and only flea and tick product to receive FDA approval for preventing infections that cause Lyme disease by killing the vector ticks, the company stated. The approval comes just as veterinarians and pet owners in many parts of the country are being warned about the potential of an increased number of Lyme disease cases in 2018. The FDA approval is based on two well-controlled laboratory studies that showed that NexGard effectively prevented the transmission of B. burgdorfei infections after dogs were infested with wild-caught I. scapularis ticks 28 days after treatment with NexGard, said the manufacturer. "Both studies measured the transmission of B. burgdorferi to dogs after exposure to infected ticks," said Zach Mills, DVM, head of US Pet Veterinary Professional Services. "All dogs treated with NexGard tested negative for B. burgdorferi infection, demonstrating that transmission was prevented as a direct result …
