New development in Valley fever vaccine for companion animalsOctober 15, 2018A novel Valley fever sub-unit vaccine for companion animals has been found by Mazen Animal Health to reduce the burden of coccidioides—the fungus that can cause Valley fever—in mice.
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20-plus clinics to participate in expanded osteosarcoma vaccine clinical trialSeptember 6, 2018Initial results of a pilot study for canine osteosarcoma vaccine are promising, prompting a larger study to test its safety and efficacy. Pharmaceutical company Aratana Therapeutics, which received conditional licensure for Live Listeria Vector (AT-014), has expanded its clinical trial to include more than two dozen veterinary oncology practice groups across the U.S. in order to receive full licensure. Conducted by the University of Pennsylvania School of Veterinary Medicine, the pilot study tested the immunotherapy treatment in 18 dogs. Those that received the vaccine lived more than twice as long as the historical, matched control group, with median survival times of 956 days compared to 423 days. The expanded clinical trial is designed to collect additional safety data for the vaccine in dogs that have undergone amputation of the affected limb and have already completed chemotherapy. If the treatment is found to be as safe and effective as it appeared in the initial clinical trial, Aratana will be given full licensure, allowing it to make the drug commercially available. Live Listeria Vector (AT-014) is created by removing harmful genes from the Listeria bacteria and then attaching markers of osteosarcoma cells. It is designed to supplement standard osteosarcoma treatment of amputation …
Assessing claims of vaccine-induced ITP, IMHAAugust 29, 2018The use of any medical interventions involves balancing risks and benefits. A treatment that has zero risks almost certainly does nothing meaningful. In the case of vaccination, the benefits are well established and often taken for granted. Many serious, even life-threatening, diseases can be prevented through vaccination. In humans, childhood vaccination is recognized as the No. 1 public health achievement of the 20th century,1 and the benefits continue to grow in the 21st.2 Although less data is available in veterinary medicine, there is no question that vaccines have been enormously effective in reducing illness and death in veterinary species as well.3-4
Ongoing quest for immunityJune 12, 2018Vaccines are a staple in preventive medicine, and every year more are added to the arsenal. Here’s what’s going on now in this sector of the profession.
Remind horse owners to safeguard against rabiesJune 7, 2018According to veterinary research published in the Journal of the American Veterinary Medical Association, the American Society for the Prevention of Cruelty to Animals, and the American Horse Council, horses are nearly four times more likely to contract rabies than dogs. Across the U.S., the majority of horses are not vaccinated for rabies and often run a higher risk of exposure than dogs, according to U.S. Department of Agriculture. "Everybody is at risk for developing rabies," said Bonnie R. Rush, DVM, MS, DACVIM, Interim Dean at Kansas State University's College of Veterinary Medicine. "[Horses are] at higher risk for being exposed probably at pasture, but being in a stall does not preclude exposure. The consequences of interacting with a horse that has rabies are significant." Horses can be exposed to rabies most commonly through bats, raccoons, foxes, and skunks. Two examples of public equine rabies cases include the 2008 Missouri State Fair; and the 2006 Tennessee Walking Horse National Celebration, which required the notification of more than 150,000 people for potential rabies exposure. Rabies is the deadliest among the five core equine diseases, which also include Eastern and Western equine encephalomyelitis, tetanus, and West Nile. Horses are continually exposed …
Zoetis launches #MyVetIsCore sweepstakes April 24, 2018 The Zoetis #MyVetIsCore Sweepstakes invites horse owners to express their appreciation for their veterinarian. Until May 22, 2018, horse owners can visit MyVetIsCore.com to enter for a chance to win weekly prizes as well as a grand prize. Eligible participants can upload a photo of their horse and veterinarian, and share why their veterinarian is "core" to their horse's health and wellness. Once a photo is uploaded, horse owners may share the graphic via their Facebook, Instagram, or Twitter account. "We launched the #MyVetIsCore Sweepstakes as a platform of encouragement—to showcase the many ways veterinarians improve the health of horses and the lives of horse owners," said Adrienne McAleer, equine marketing innovation manager for the company. "Equine wellness requires a dedicated team, from efficacious products to the trusted bond between horse owners and their veterinarians, to help protect horses." "It's vital that horse owners work closely with their veterinarian to help protect their horse from grave disease risks," said Kevin Hankins, DVM, senior equine technical services veterinarian for Zoetis. "Providing this level of protection begins with annual vaccination against the five core diseases. More than diseases, they can be a death sentence, and this is a threat we do …
AHI studies economic, social contributions of animal health industryMarch 15, 2018The Animal Health Institute has released its findings from a first-of-its-kind study into the economic and social contributions of the animal health industry, which also covers household pets. The report examines the role the companies that produce pharmaceuticals, vaccines, and flea and tick products play in the U.S. economy and beyond. Key report findings include: Household Pets – More than 67 percent of American households, or 84.6 million, own nearly 400 million companion animals. This includes dogs, cats, horses, birds, fish, horses, and more. Pets by Type – Nearly half of pet-owning households include a dog while over one-third own a cat, for a total of 89.7 million dogs and 94.2 million cats. There are between 100,000 and 200,000 service animals, including those who assist the blind and disabled (but not including police, forensic, or military dogs). Almost all—95 percent—of dog and cat owners view their pets as members of their family. Spending on Pets – Americans spent more than $75.5 billion on their pets in 2016, with an average total household spend of $892 on pet food, veterinary services, supplies, and other services. As pet owners look for solutions to increase the length and quality of life for …
Dog flu goes viralMarch 13, 2018While it’s unknown how many dogs have been affected—canine influenza isn’t a reportable disease in the U.S., although it is in Canada—the figures are underreported, said Cynda Crawford, DVM, clinical assistant professor at the University of Florida College of Veterinary Medicine.
Boehringer Ingelheim, Merial launch Recombitek Oral BordetellaFebruary 14, 2018Merial, now part of Boehringer Ingelheim, has launched Recombitek Oral Bordetella, an oral vaccine shown to be effective against canine infectious tracheobronchitis caused by Bordetella bronchiseptica, the company reported. Clinical studies suggest that as a mucosal vaccine, it offers dogs a robust immune response after a single dose, according to the manufacturer. B. bronchiseptica, one of the primary pathogens responsible for canine infectious respiratory disease complex, is unique in its ability to evade the immune system for weeks to months. During this time, a dog that appears clinically normal could be exposing other dogs. "For many dogs, oral delivery may mean a less stressful experience without the unpleasant sneeze backs of alternative vaccines delivered through the nose," said Zach Mills, DVM, executive director of Boehringer Ingelheim's U.S. Pet Vet Veterinary Professional Services. "The packaging's flip-top vial cap allows for easy opening by veterinary staff, and the safe, needle-free pipette simplifies the vaccination process while reducing risk of injury." Recombitek Oral Bordetella is administered into the dog's buccal cavity. Recombitek vaccines are backed by the Pet Vaccines Customer Satisfaction Guarantee. Visit boehringer-ingelheim.com for more information.
Strangles vaccine within reach for horsesFebruary 12, 2018Scientists from the Animal Health Trust (AHT), the Swedish University of Agricultural Sciences, the Karolinska Institute, and Intervacc AB, have developed a new protein-based vaccine to protect horses from strangles. Strangles, caused by Streptococcus equi bacteria, leads to large pus-filled abscesses in horses' throat and neck. The research was recently published in Vaccine. " … Our Strangvac vaccine protected over 80 percent of horses from this dreadful disease," said Jan-Ingmar Flock, Ph.D., CEO of Intervacc AB, the company that produced the vaccine. "Strangles is a scourge of the equine world and the development of Strangvac has the potential to prevent many thousands of horses from falling ill each year." "Strangvac is an extremely exciting vaccine," said Dr. Andrew Waller, head of bacteriology at AHT. "The vaccine was designed using information from sequencing the DNA of Streptococcus equi and highlights the potential that the genome-era heralds for improving the health of animals and people. Improving the health of horses is a core aim of the Animal Health Trust and we are proud to have helped make this vaccine a reality towards finally breaking the hold this disease currently has on our …
