Remind horse owners to safeguard against rabiesJune 7, 2018According to veterinary research published in the Journal of the American Veterinary Medical Association, the American Society for the Prevention of Cruelty to Animals, and the American Horse Council, horses are nearly four times more likely to contract rabies than dogs. Across the U.S., the majority of horses are not vaccinated for rabies and often run a higher risk of exposure than dogs, according to U.S. Department of Agriculture. "Everybody is at risk for developing rabies," said Bonnie R. Rush, DVM, MS, DACVIM, Interim Dean at Kansas State University's College of Veterinary Medicine. "[Horses are] at higher risk for being exposed probably at pasture, but being in a stall does not preclude exposure. The consequences of interacting with a horse that has rabies are significant." Horses can be exposed to rabies most commonly through bats, raccoons, foxes, and skunks. Two examples of public equine rabies cases include the 2008 Missouri State Fair; and the 2006 Tennessee Walking Horse National Celebration, which required the notification of more than 150,000 people for potential rabies exposure. Rabies is the deadliest among the five core equine diseases, which also include Eastern and Western equine encephalomyelitis, tetanus, and West Nile. Horses are continually exposed …
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Zoetis launches #MyVetIsCore sweepstakes April 24, 2018 The Zoetis #MyVetIsCore Sweepstakes invites horse owners to express their appreciation for their veterinarian. Until May 22, 2018, horse owners can visit MyVetIsCore.com to enter for a chance to win weekly prizes as well as a grand prize. Eligible participants can upload a photo of their horse and veterinarian, and share why their veterinarian is "core" to their horse's health and wellness. Once a photo is uploaded, horse owners may share the graphic via their Facebook, Instagram, or Twitter account. "We launched the #MyVetIsCore Sweepstakes as a platform of encouragement—to showcase the many ways veterinarians improve the health of horses and the lives of horse owners," said Adrienne McAleer, equine marketing innovation manager for the company. "Equine wellness requires a dedicated team, from efficacious products to the trusted bond between horse owners and their veterinarians, to help protect horses." "It's vital that horse owners work closely with their veterinarian to help protect their horse from grave disease risks," said Kevin Hankins, DVM, senior equine technical services veterinarian for Zoetis. "Providing this level of protection begins with annual vaccination against the five core diseases. More than diseases, they can be a death sentence, and this is a threat we do …
AHI studies economic, social contributions of animal health industryMarch 15, 2018The Animal Health Institute has released its findings from a first-of-its-kind study into the economic and social contributions of the animal health industry, which also covers household pets. The report examines the role the companies that produce pharmaceuticals, vaccines, and flea and tick products play in the U.S. economy and beyond. Key report findings include: Household Pets – More than 67 percent of American households, or 84.6 million, own nearly 400 million companion animals. This includes dogs, cats, horses, birds, fish, horses, and more. Pets by Type – Nearly half of pet-owning households include a dog while over one-third own a cat, for a total of 89.7 million dogs and 94.2 million cats. There are between 100,000 and 200,000 service animals, including those who assist the blind and disabled (but not including police, forensic, or military dogs). Almost all—95 percent—of dog and cat owners view their pets as members of their family. Spending on Pets – Americans spent more than $75.5 billion on their pets in 2016, with an average total household spend of $892 on pet food, veterinary services, supplies, and other services. As pet owners look for solutions to increase the length and quality of life for …
Dog flu goes viralMarch 13, 2018While it’s unknown how many dogs have been affected—canine influenza isn’t a reportable disease in the U.S., although it is in Canada—the figures are underreported, said Cynda Crawford, DVM, clinical assistant professor at the University of Florida College of Veterinary Medicine.
Boehringer Ingelheim, Merial launch Recombitek Oral BordetellaFebruary 14, 2018Merial, now part of Boehringer Ingelheim, has launched Recombitek Oral Bordetella, an oral vaccine shown to be effective against canine infectious tracheobronchitis caused by Bordetella bronchiseptica, the company reported. Clinical studies suggest that as a mucosal vaccine, it offers dogs a robust immune response after a single dose, according to the manufacturer. B. bronchiseptica, one of the primary pathogens responsible for canine infectious respiratory disease complex, is unique in its ability to evade the immune system for weeks to months. During this time, a dog that appears clinically normal could be exposing other dogs. "For many dogs, oral delivery may mean a less stressful experience without the unpleasant sneeze backs of alternative vaccines delivered through the nose," said Zach Mills, DVM, executive director of Boehringer Ingelheim's U.S. Pet Vet Veterinary Professional Services. "The packaging's flip-top vial cap allows for easy opening by veterinary staff, and the safe, needle-free pipette simplifies the vaccination process while reducing risk of injury." Recombitek Oral Bordetella is administered into the dog's buccal cavity. Recombitek vaccines are backed by the Pet Vaccines Customer Satisfaction Guarantee. Visit boehringer-ingelheim.com for more information.
Strangles vaccine within reach for horsesFebruary 12, 2018Scientists from the Animal Health Trust (AHT), the Swedish University of Agricultural Sciences, the Karolinska Institute, and Intervacc AB, have developed a new protein-based vaccine to protect horses from strangles. Strangles, caused by Streptococcus equi bacteria, leads to large pus-filled abscesses in horses' throat and neck. The research was recently published in Vaccine. " … Our Strangvac vaccine protected over 80 percent of horses from this dreadful disease," said Jan-Ingmar Flock, Ph.D., CEO of Intervacc AB, the company that produced the vaccine. "Strangles is a scourge of the equine world and the development of Strangvac has the potential to prevent many thousands of horses from falling ill each year." "Strangvac is an extremely exciting vaccine," said Dr. Andrew Waller, head of bacteriology at AHT. "The vaccine was designed using information from sequencing the DNA of Streptococcus equi and highlights the potential that the genome-era heralds for improving the health of animals and people. Improving the health of horses is a core aim of the Animal Health Trust and we are proud to have helped make this vaccine a reality towards finally breaking the hold this disease currently has on our …
Registration open for Veterinary Biologics Training ProgramJanuary 17, 2018The Institute for International Cooperation in Animal Biologics (IICAB) has opened registration for the Veterinary Biologics Training Program, which will be held May 14-18 in Ames, Iowa. The program provides an overview of the U.S. Department of Agriculture's regulatory process for assuring the purity, safety, potency, and efficacy of veterinary biologics (vaccines, bacterins, antisera, diagnostic kits, and other products of biological origin). During the weeklong program, staff from the Center for Veterinary Biologics (CVB) at the USDA's Animal & Plant Health Inspection Service provides information on the requirements and processes for licensing/registration and testing of veterinary biological products. The inspection and compliance process for production, release, and post-marketing surveillance of veterinary biological products is also covered in both lectures and workshops, IICAB said. Professionals working in the veterinary biologic industry, researchers developing biologics, and regulatory personnel are encouraged to attend to learn about current CVB requirements. More than 2,700 individuals have attended the program since it was launched in 1996, including 750 individuals from 90-plus countries. The program is organized by IICAB and is co-sponsored by CVB and the Iowa State University College of Veterinary Medicine. Individuals interested in an introduction or refresher in the ever-changing field of immunology …
Aratana Therapeutics secures USDA conditional license for canine osteosarcoma vaccineJanuary 10, 2018Aratana Therapeutics announced that its canine osteosarcoma vaccine, Live Listeria Vector (AT-014), has been granted a conditional license by the USDA Center for Veterinary Biologics for the treatment of dogs diagnosed with osteosarcoma, 1 year of age or older. The vaccine is a novel immunotherapy developed by using a listeria-based antigen delivery system licensed from Advaxis Inc. "Osteosarcoma is the most common primary bone tumor in dogs and, since there haven't been advances to raise the standard of care in nearly 20 years, dogs often face a poor prognosis," said Ernst Heinen, DVM, Ph.D., chief development officer of Aratana Therapeutics. "We are hopeful that our canine osteosarcoma vaccine will be a new tool for veterinary oncologists to prolong survival in dogs with osteosarcoma." According to the company, the vaccine is a lyophilized formulation of a modified live, attenuated strain of listeria that activates cytotoxic T-cells. The therapeutic expresses a tumor-associated antigen that directs T-cells to fight cancer cells, even after the bacteria are cleared; the therapeutic capitalizes on the dog's immune system and its ability to attack bacterial infections, redirecting it to fight cancer cells, the company stated. Data from a clinical study …
Synthetic Genomics, Ceva partner to develop livestock vaccinesNovember 1, 2017 Synthetic Genomics Inc. announced that it has partnered with Ceva Santé Animale to utilize Synthetic Genomics' next-generation synthetic RNA replicon platform to develop vaccines for livestock. Synthetic Genomics' RNA replicons are programed to deliver genetic instructions to a body's own cells to unleash a powerful immune response against a specific disease, the company said. These RNA replicons carry the genetic code for a self-replication engine as well as antigens that signal for an immune response. The self-amplifying, RNA-based vaccine triggers rapid and immediate antigen expression within host cells, which induces strong T cell and B cell responses. These fully synthetic vaccines have lower dose requirements and simplified manufacturing compared to traditional vaccine approaches, according to the announcement. "We have made tremendous progress to date in programming RNA to develop next-generation vaccines that are multigenic, tunable and, most importantly, scalable for commercially competitive markets such as animal health," said Synthetic Genomics CEO Dr. Oliver Fetzer. "This partnership with Ceva, a leader in animal health, highlights the promise in deploying our synthetic biology capabilities to build RNA systems capable of improving global health in a variety of ways." Financial terms of the agreement were not …
Canine rabies vaccination promises unexpected benefitsSeptember 28, 2017 New research funded by Morris Animal Foundation shows the rabies vaccine may have a positive impact on overall canine health and is associated with a decrease in death from all causes. Darryn Knobel, BVSc MSc MRCVS PhD, associate professor of epidemiology and population health at Ross University School of Veterinary Medicine recently published his research results in the journal Vaccine. What the findings show The study found that vaccination reduces the risk of death from any cause by 56 percent in dogs 0 to 3 months of age. While all dogs had decreased mortality, the percentage decrease was highest in young dogs, with the effect diminishing over time. Dr. Knobel's study area incorporates an impoverished region of South Africa, where infectious diseases, including rabies, are an ever-present threat to humans and dogs. The research team concluded that the decrease in mortality couldn't be explained by a reduction in deaths due to rabies alone. "This led us to propose that the vaccine may have a non-specific protective effect in dogs, perhaps through boosting the immune system to provide enhanced defense against other, unrelated diseases," said Knobel. "A similar phenomenon has been observed in children, although …