The purebred paradoxMay 11, 2018Purebreds are overrepresented in popular culture. Though a few of the Hollywood elite may proudly promenade their “rescue mutts” as they shop Rodeo Drive, most lay claim to full-blooded epitomes of dogdom.
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Kindred Biosciences' Mirataz commercially available in U.S.May 9, 2018Update: this product is now commercially available in the U.S. Kindred Biosciences Inc. has received approval from the U.S. Food & Drug Administration for Mirataz (mirtazapine transdermal ointment) for the management of weight loss in cats. Mirtazapine, which blocks specific serotonin and histamine receptors that play a role in appetite and nausea, demonstrated a 3.9 percent increase in body weight in cats with unintended weight loss in as little as 14 days, according to San Francisco-based Kindred. To help improve owner and patient compliance, Mirataz will be available in a topical formulation applied to the inner pinna of a cat's ear. Research shows daily topical application for 14 days resulted in measurable plasma concentrations of mirtazapine in cats, the manufacturer stated. Mirataz offers the confidence of a product approved by the U.S. Food & Drug Administration Center for Veterinary Medicine, convenience of transdermal application, Good Manufacturing Practice (cGMP) production quality, known stability, manufacturer technical support, and a practical way to manage feline weight loss without administration of oral medication, according to Valentine S. Williams, DVM, DACVS, director of veterinary affairs at Kindred Biosciences.
The trials of therapeutic dietsMay 8, 2018Client misconceptions and behaviors can be the biggest barrier to successful outcomes when prescribing therapeutic diets for dermatologic disease.
High-tech remote health monitoringMay 7, 2018A cat visits the litterbox more often and for a longer duration than normal. A dog makes extra visits to the water bowl and is up and down a bit more often than usual.
How to fix oronasal fistulasMay 4, 2018This month’s column discusses the surgical approach to treatment of the most common manifestation of oronasal fistulas: those that occur in the area of the maxillary canine tooth in dogs.
Is a cure for IMHA near?May 3, 2018The image of a straight line neatly sums up the frustration of treating dogs afflicted with immune-mediated hemolytic anemia (IMHA), according to Andrew Mackin, BVMS, DVSc, FANZCVSc, DACVIM, professor and head of the Department of Clinical Sciences at Mississippi State University College of Veterinary Medicine.
Soothe the itchMay 1, 2018Whether it’s from allergies, bacterial infections, or external parasites such as fleas or mites, pruritus is easily among the top 10 problems veterinarians see in dogs and cats. Atopic disease alone is the No. 1 most common condition in dogs and the eighth most common in cats.
Ticks' increasing threatApril 25, 2018Masters of ride-sharing well before Uber and Lyft came along, ticks hitch rides with white-tailed deer, migrating birds, and other animals, making their way to locales where they didn’t exist in the past. Now, one or more tick species are found in every state, including Alaska and Hawaii.
MAF awards Penn $775K to test osteosarcoma immunotherapy vaccine in dogsApril 20, 2018Morris Animal Foundation (MAF) has awarded a $775,000 grant to the University of Pennsylvania to test a vaccine that could improve longevity and quality of life for dogs with osteosarcoma. The research team will conduct clinical trials to evaluate a novel immunotherapy treatment that combines a molecule expressed by cancer cells with a modified live form of Listeria monocytogenes. A pilot study demonstrated this combination elicited a powerful, targeted immune response directed against osteosarcoma cells in patients suffering from this type of cancer. "This could be an incredible breakthrough in the fight against osteosarcoma, a highly aggressive and deadly cancer," said Kelly Diehl, DVM, DACVIM (SAIM), senior scientific programs and communications adviser at MAF. "For the last 50 years, Morris Animal Foundation has been funding cancer studies, and this is one of the largest, single grants we have ever awarded. The results of the pilot study were so compelling, that we knew we had to support this research team and their progression to a clinical trial." The vaccine, created by removing harmful genes from the Listeria bacteria and then attaching markers of osteosarcoma cells, supplements standard osteosarcoma treatment of amputation and chemotherapy by attacking cancer cells that …
As U.S. pet obesity balloons, vets, owners talk diet, nutritionApril 20, 2018The dog and cat pet obesity epidemic in the U.S. continues to grow, according to the Association for Pet Obesity Prevention (APOP). In the organization's 2017 annual clinical survey, 56 percent of dogs and 60 percent of cats were classified as overweight or obese by their veterinarian. In 2016, APOP found 54 percent of dogs and 59 percent of cats were overweight or obese. In the survey, pet owners and veterinary professionals were questioned about diet and nutrition, sources of pet food advice, the benefits of corn, dry versus canned, whether pet food has improved, the best sources of pet dietary recommendations, and more. Among the findings: 58 percent of pet owners and 54 percent of veterinary professionals reported having tried to help their own pet lose weight via low-calorie and weight loss diets combined with increased exercise. 25 percent of pet owners and 43 percent of veterinary professionals said they were "too busy" to exercise their dog; 21 percent of pet owners and 19 percent of veterinary professionals cited behavior issues as a barrier. Inadequate access to exercise areas and physical limitations of the owner and pet rounded out the reported challenges. 48 percent of …