VPN Plus+ ExclusiveCBD or CBD and THC combined?May 29, 2020While cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) are both phytocannabinoids derived from cannabis plants, differences in their chemical structures allow each to interact with unique receptors, resulting in distinct molecular targets and physiological effects. Namely, THC shows high affinity toward CB1 receptors, which are present in central and peripheral neurons, resulting in the euphoric effect commonly attributed to cannabis intoxication. In contrast, CBD does not bind CB1 at relevant concentrations and is nonintoxicating. Instead, CBD interacts, to various degrees, with other receptors (agonism at TRPV1 and 5-HT1A, antagonism at TNFα, GPR55, and GPR18), which may be relevant for its suggested therapeutic effects. Practical considerations Recently, CBD- and THC-containing products for people and pets have become more widely available, especially in jurisdictions that have passed legislation allowing the sale of such items intended for human use. Evolving regulatory frameworks and social perceptions have also renewed interest in the potential therapeutic properties of cannabinoids for animals. Importantly, there are no authorized veterinary drugs containing cannabinoids in the U.S., and any state laws permitting the use of medical cannabis do not apply to use in animals. Increasingly, the veterinary profession is being asked to weigh in on the potential roles of CBD and …
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Is a heartworm vaccine on the horizon?May 21, 2020Protecting dogs from deadly parasites and combating drug resistance to heartworm medications are the central goals behind a new Morris Animal Foundation-funded study.
Fecal microbiome testing: Is the research reliable to ensure a healthy pet?May 7, 2020While enthusiasm for new discoveries and hypotheses is a necessary part of scientific progress, the premature application of these to clinical patients can be harmful.
Generic equine sedative OKed by FDAMay 1, 2020Detomidine hydrochloride is used to manage pain in both mature horses and yearlings when undergoing minor surgical procedures, such as the repairing of skin lacerations, as well as diagnostics.
Southeast U.S. "hotbed" for heartworms, warns AHSApril 21, 2020While the COVID-19 pandemic remains top of mind in the U.S. and beyond, the American Heartworm Society (AHS) is reminding veterinarians to stay mindful of heartworm prevention.
New guidelines help ensure heartworm safety, prevention amid COVID-19April 7, 2020Conditions under which a veterinarian can delay annual heartworm tests during the COVID crisis is just one of the topics covered in new recommendations released by AHS.
Recalled human anti-ulcer drug used in veterinary medicineApril 2, 2020A human anti-ulcer drug also used in veterinary medicine has been recalled by the U.S. Food and Drug Administration (FDA) after the agency discovered it might contain unsafe levels of a probable human carcinogen.
Cannabis and its role in the endocannabinoid biomeMarch 31, 2020With the recent interest and rapid growth of the cannabis industry, an understanding of the ECB is the first step toward developing a foundation in cannabis science.
Biopharma company sells feline weight-loss med for $43MMarch 31, 2020A mirtazapine transdermal ointment, used for the management of weight loss in cats, has just changed pharmaceutical hands in a multimillion dollar deal.
Alternative treatment for deadly foal pneumonia revealedMarch 30, 2020Equine veterinarians may soon be equipped with a method for treating pneumonia in foals that does not promote multidrug-resistant bacteria.
